Results 21 to 30 of about 1,741 (234)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Ivory and religious statues in the Philippines today

open access: yesPachyderm, 2016
From 2009 corrupt officials in the Philippines were reported to have stolen tonnes of African elephant tusks that customs had confiscated in transit from Africa to China.
Lucy Vigne
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

REFLECTION OF THE RIVALRY BETWEEN THE TWO ANCIENT KURDISH NATIONS, KASSITE AND MITANNI, ON THE ART OF SEALING AND SCULPTURE IN THE SECOND MILLENNIUM BC

open access: yesگۆڤارا زانستێن مرۆڤایەتی یا زانكۆیا زاخۆ
The Kassites and Mitanni are considered ancient Kurdish nations. In the second millennium BC, there was a phenomenon of rivalry in ancient Kurdistan, especially between the Kassite and Mitannian political powers.
Salah Jehwar, Imad Mohammad
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Anatomy Lessons: Michele Beevors as Eco-Political Agent

open access: yesLagoonscapes
This article responds to the large scale sculptural work by eco-political artist Michele Beevors, whose work has recently been extensively exhibited in New Zealand, Australia, and Austria.
Schmidt, Leoni
doaj   +1 more source

Autour de la Vache de Myron : de l’éloge de l’opus nobile à la réflexion sur les genres et les sujets en poésie

open access: yesAitia, 2020
This article studies the possible meaning of Posidippus’ praise of Myron's Cow, a poem which occupies a central position in the andriantopoiika (epigrams on bronze statues) of the Macedonian poet. Even if Myron’s original represented a cow destinated for
Évelyne Prioux
doaj  

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

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