Results 121 to 130 of about 641,866 (350)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Stimulus, effects attention and reading performance : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in applied psychology at Massey University [PDF]

open access: yes, 1976
This investigation reports an experimental study on the effects different stimulus characteristics have on attention and subsequent reading performance with "good" and "poor" readers.
McRae, Garth Cranston
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Wild boar behaviour during live-trap capture in a corral-style trap: implications for animal welfare [PDF]

open access: gold, 2020
Åsa Fahlman   +5 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Spartan Daily, November 13, 1998 [PDF]

open access: yes, 1998
Volume 111, Issue 54https://scholarworks.sjsu.edu/spartandaily/9342/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

PELAYANAN KESEHATAN SAPI DI BANJAR SAMUAN KAWAN DAN SAMUAN KANGIN, DESA CARANGSARI, KECAMATAN PETANG, KABUPATEN BADUNG

open access: yesBuletin Udayana Mengabdi, 2014
Animal health service is one of key factors to be successful in animal breeding. This program include curativeaction for animal illness, sanitation program and vaccination as a preventive program.
I W AYAN SUARDANA
doaj  

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