Results 1 to 10 of about 4,797,624 (302)

Alternatives to animal testing: A review. [PDF]

open access: yesSaudi Pharm J, 2015
The number of animals used in research has increased with the advancement of research and development in medical technology. Every year, millions of experimental animals are used all over the world. The pain, distress and death experienced by the animals during scientific experiments have been a debating issue for a long time. Besides the major concern
Doke SK, Dhawale SC.
europepmc   +3 more sources

How to Boycott Animal Testing

open access: yesVoices in Bioethics, 2014
Animal rights extremism is no stranger to the news headlines, with involved individuals moving from attacking large corporations to intimidating individual researchers.
Marilyn Eshikena
doaj   +2 more sources

Evaluation of mutagenicity of zinc oxide nanoparticles by Pig-a mutation assay in vivo

open access: yesShanghai yufang yixue, 2022
ObjectiveThe genotoxicity of zinc oxide nanoparticles (ZnO NPs) in rats was determined by Pig⁃a mutation assay in vivo.MethodsCombined with 28-day oral toxicity test, male SD rats were given ZnO NPs by oral administration for 28 days, at doses of 0, 14 ...
CHENG Xueqing   +4 more
doaj   +1 more source

Measuring respiratory and heart rate using a fiber optic interferometer: A pilot study in a neonate model

open access: yesFrontiers in Pediatrics, 2022
IntroductionThe study aim was to test the safety and efficacy of a pad with optic fibers developed for monitoring newborn respiratory rate (RR) and heart rate (HR).MethodsThirty New Zealand White rabbits were included, divided by weight into three groups.
Jakub Cubík   +13 more
doaj   +1 more source

Modernizing Medical Research to Benefit People and Animals

open access: yesAnimals, 2022
In the context of widespread public and political concern around the use of animals in research, we sought to examine the scientific, ethical and economic arguments around the replacement of animals with New Approach Methodologies (NAMs) and to situate ...
Isobel Hutchinson   +2 more
doaj   +1 more source

Toll-like receptor 5-mediated IL-17C expression in intestinal epithelial cells enhances epithelial host defense against F4+ ETEC infection

open access: yesVeterinary Research, 2019
Enterotoxigenic Escherichia coli (ETEC) are an important cause of post-weaning diarrhea (PWD) in piglets. The IL-17 cytokine family is well known to play important roles in the host defense against bacterial infections at the mucosa.
Yu Luo   +9 more
doaj   +1 more source

“It’s Not Good for the Animals, but I Think It Should Be Done”—Using Focus Group Interviews to Explore Adolescent Views on Animal Experimentation

open access: yesAnimals, 2022
The present study focused on an in-depth analysis of adolescents’ (aged 15–16) attitudes towards animal experimentation. Focus group interviews were conducted to gain a deeper understanding regarding the ethical considerations of this age group. The data
Sonja M. Enzinger, Christian Dürnberger
doaj   +1 more source

Bioethics and animal testing. A review of scientific praxis in Mexico

open access: yesRevista Colombiana de Bioética, 2018
This study examines the experimental use of non-human animals in Mexico from a bioethical approach. For this purpose, a survey was applied to researchers who develop research lines with animals (specifically chordates) to know the ethical and technical ...
Luis Alberto Contreras Armas   +3 more
doaj   +1 more source

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