Results 121 to 130 of about 1,812,118 (303)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Physical and chemical characterizations of a reference e-cigarette used in animal testing. [PDF]

Sci Rep, 2023
Soulet S, Constans L, Quinty V.
europepmc   +1 more source

Animal tests inescapable [PDF]

Nature, 2008
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Author Correction: Physical and chemical characterizations of a reference e-cigarette used in animal testing. [PDF]

Sci Rep, 2023
Soulet S, Constans L, Quinty V.
europepmc   +1 more source

Report on qualitative concept tests (D.6.2) [PDF]

, 2013
This report presents the findings of the qualitative concept tests, conducted as a part of WP6 of the SUMMER project. The main objective of the study is to explore consumers’ response to improved animal welfare standards in organic production systems ...
Marian, Livia
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Cytotoxicity assay as a potential alternative method for animal testing for batch release of Italian fish autogeneous vaccines. [PDF]

Open Vet J, 2023
Di Paolo A, Anzalone L, Pellegrini M, Severi G, Cagiola M.   +4 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Protocol for single-use Ambu aScope-based minimally invasive bronchoalveolar lavage collection in pigs

STAR Protocols
Summary: Here, we present a protocol for collecting bronchoalveolar lavage (BAL) samples from live pigs using a single-use Ambu aScope. We describe the steps for animal preparation, BAL collection, and sample handling, including downstream analysis, to ...
Piyush Baindara, Dinata Roy, Addison K. Byrne, Jonathan A. Green   +3 more
doaj   +1 more source