Results 41 to 50 of about 1,812,118 (303)

Microfluidics : the fur-free way towards personalised medicine in cancer therapy [PDF]

, 2016
Microfluidic technology has great potential for complementing and, in some instances, replacing the use of animal models in the testing of medicines and in developing personalised treatments for cancer patients.
Bower, Ruth, Dawson, Amy, Green, Vicky, Greenman, John   +3 more
core  

A mucosa-mimetic material for the mucoadhesion testing of thermogelling semi-solids [PDF]

, 2017
Mucosa-mimetic materials are synthetic substrates which aim to replace animal tissue in mucoadhesion experiments. One potential mucosa-mimetic material is a hydrogel comprised of N-acryloyl-d-glucosamine and 2-hydroxyethylmethacrylate, which has been ...
Bruschi, Marcos L., Cook, Michael T., da Silva, Jéssica Bassi, Khutoryanskiy, Vitaliy V.   +3 more
core   +3 more sources

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]

, 2014
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh, Ausar, Salvador F, Brookes, Roger H, Dockrell, Hazel M, Ha, Yukyung, Hakimi, Jalil, Hasija, Manvi, Rahman, Nausheen, Smith, Steven G, Todryk, Stephen M   +9 more
core   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Verjüngungsforschung Anfang des 20. Jahrhunderts

Recherches Germaniques
At the beginning of the 20th century, rejuvenation became fashionable. The background to this was the discovery of hormones and the observation of a connection between sex hormones and vitality. Animals had a central role in endocrinology research.
Stefan Hecht
doaj   +1 more source

A Clinical and Epidemiological Investigation of the First Reported Human Infection With the Zoonotic Parasite Trypanosoma evansi in Southeast Asia [PDF]

, 2016
Background. Trypanosoma is a genus of unicellular parasitic flagellate protozoa. Trypanosoma brucei species and Trypanosoma cruzi are the major agents of human trypanosomiasis; other Trypanosoma species can cause human disease, but are rare.
Baker, S, Berto, A, Campbell, JI, Carrique-Mas, J, Chalermwong, P, Desquesnes, M, Franco, JR, Herder, S, Jittapalapong, S, Le, BC, Nga, TVT, Ngo, TH, Ngo, TT, Nguyen, CT, Nguyen, KC, Nguyen, PHL, Nguyen, VC, Nguyen, VMH, Nguyen, VVC, Rabaa, MA, Tam, PTT, Thwaites, GE, Tran, TH, Wills, B, Yacoub, S, Yimming, B   +25 more
core   +1 more source

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Testing, Testing 1,2,3 [PDF]

, 2012
Overview: Since childhood, most human beings have been raised on the foundation of accepting and adhering to the “Golden Rule” in everyday aspects of life.
Hogenkamp, Eugenia
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source