Results 71 to 80 of about 4,797,624 (302)
Frontiers in Bioengineering and BiotechnologyIntroductionHemorrhage remains the leading cause of preventable death on the battlefield. The most effective means to increase survivability is early hemorrhage control and fluid resuscitation.
Eric J. Snider +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2019 This internet resource contains issues published throughout multiple yearsRegional Vet Meetings -- Kansas Added to the 2019 Vesicular Stomatitis Roster -- USDA-APHIS to Revisit ADT Guidelines -- FMD Exercise Set For December -- ASF Multi-State Drill Held
Kansas Animal Health
core
, 2021 Farm management can directly and indirectly affect animal care. We explored how farm management affected animal care on two large dairy farms in China (anonymized as Farm A and Farm B).
Weary, Daniel M. +7 more
core +1 more source
Frontiers in Genetics, 2018 Despite Bisphenol-A (BPA) being subject to extensive study, a thorough understanding of molecular mechanism remains elusive. Here we show that using weighted gene correlation network analysis (WGCNA), which takes advantage of a graph theoretical approach
Alexandra Maertens +5 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Path dependency and the rescuing of the biomedical research enterprise
Frontiers in Medical TechnologyIn 2025, three U.S. agencies within the Department of Health and Human Services (FDA, NIH, CDC) alongside EPA and the Departments of the Navy and Veterans Affairs, began substituting animal testing applications with reliable, human-relevant methods.
Zaher Nahle, Zaher Nahle
doaj +1 more source
Annals of Clinical Microbiology and Antimicrobials, 2017 Background Staphylococcus aureus is the predominant bacterium responsible for various diseases in animals and humans. Preventive strategies could be better implemented by understanding the prevalence, genetic patterns, and the presence of enterotoxin and
Vishnu Sharma +5 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source