Scoring shoulder ulcers in breeding sows – is a distinction between substantial and insubstantial animal welfare-related lesions possible on clinical examination? [PDF]
, 2019 Daniel M. Meyer +4 more
openalex +1 more source
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
Animal Welfare Certification For Laying Hens: Compliance With The Legal Prohibition Of Mistreatment In Brazil [PDF]
, 2019 Yuri Fernandes Lima
openalex +1 more source
The impact of organic livestock standards on animal welfare – a questionnaire survey of advisors, inspectors and veterinarians [PDF]
, 2002 This report was presented at the UK Organic Research 2002 Conference. A questionnaire survey of organic sector body inspectors, organic advisors and farm animal veterinarians was conducted to examine the respondents’ perceptions of the ability of the ...
Hovi, Malla +5 more
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Animal Welfare in Science Depends on Veterinarians [PDF]
, 2016 Heather Rally
openalex +1 more source
Labour Management for Profit and Welfare in Extensive Sheep Farming [PDF]
Sheep welfare is an emerging topic in research and food marketing, and recent studies suggest that farm labour is a key factor for both animal welfare and productivity in extensive sheep farming systems, although little research has been done into labour
Edwards, Ian E. +3 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Brand Information Mitigating Negative Shocks on Animal Welfare: Is It More Effective to “Distract†Consumers or Make Them Aware? [PDF]
To create and sustain a competitive advantage in markets that increasingly value animal welfare attributes, meat companies need to meet public and private production standards while communicating to final consumers through their brands.
Calantone, Roger J. +3 more
core +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source