Results 141 to 150 of about 709,968 (295)
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Ciencia y AgriculturaLas infecciones de sitio quirúrgico (ISQ) son un tipo de afecciones asociadas a la atención en salud (IAAS) que ocurre después de una intervención quirúrgica, en una zona del cuerpo donde se llevó a cabo una incisión, afectando piel, tejidos y/o órganos,
MELISA DANIELA MUNEVAR ROMERO +5 more
doaj
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Arquivos Brasileiros de Cardiologia, 2010 FUNDAMENTO: A transposição corrigida das grandes artérias frequentemente evolui com disfunção ventricular direita. O preparo ventricular para a correção anatômica em pacientes adultos apresenta resultados desapontadores.
Leonardo Augusto Miana +9 more
doaj
Detección de virus Chikungunya y Zika en animales: Revisión sistemática y meta-análisis [PDF]
, 2019 La primera descripción de muchas enfermedades arbovirales se produjo en primer lugar en animales, incluidos múltiples alfavirus y flavivirus, como el Chikungunya (CHIKV) y el Zika (ZIKV), respectivamente.
Jiménez Cruz, Stephania
core
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Cuando los animales son los "otros". Reflexiones en torno al especieísmo y su incorporación al currículum de la educación ciudadana [PDF]
, 2016 El objetivo principal de nuestro texto es reflexionar en torno a qué lugar ocupa la cuestión en relación a los animales en el currículo de la Didáctica de las Ciencias Sociales.
Triviño Cabrera, Laura
core
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source