Results 171 to 180 of about 3,673,245 (381)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

ANIMALES E INCAS EN EL OESTE TINOGASTEÑO (CATAMARCA, ARGENTINA)

open access: yesLatin American Antiquity, 2017
Juan Pablo Miyano   +3 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

La protección jurídica de los animales en el Derecho positivo español ¿algo más que mera protección? [PDF]

open access: yes, 2015
Comunicación presentada y defendida oralmente en el Congreso Internacional Ambiente y "Derecho". Entre responsabilidad y participación el día 14 de noviembre de 2015 en la sesión "Gestión de los recursos, alimentación y seguridad ambiental".La ...
López García, Mabel
core  

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

INFECCIONES ZOONÓTICAS CAUSADAS POR LEVADURAS DEL GÉNERO Malassezia: UNA REVISIÓN

open access: yesRevista U.D.C.A Actualidad & Divulgación Científica, 2016
Las zoonosis son enfermedades que se transmiten de forma natural entre los animales vertebrados y el hombre. Existe un gran número de enfermedades bacterianas, virales y parasitarias, que son transmitidas de los animales a los humanos, mientras que pocas
Juan C Galvis Marín   +1 more
doaj  

Reconocimiento legal de la calidad de seres sintientes a los animales de compañía para prevenir el maltrato animal en Colombia [PDF]

open access: yes, 2017
Artículo de reflexiónEl presente artículo de investigación realiza un análisis acerca de del reconocimiento de la calidad de seres sintientes que se le ha otorgado a los animales de compañía con el fin de garantizarles algunos derechos e igualmente ...
Díaz-Guevara, Angélica María
core  

Home - About - Disclaimer - Privacy