Results 171 to 180 of about 3,149,439 (301)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

[Transcatheter resolution of a giant congenital coronary fistula in a child]. [PDF]

Arch Cardiol Mex
De la Cruz-Pelayo J, Colín-Ortiz JL, Camacho-Reyes L, Silva-Estrada JA.   +3 more
europepmc   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Left atrial isomerism, L-looped single ventricle and conduction disorders. [PDF]

Arch Cardiol Mex
Katekaru-Tokeshi DI, Alvitres-Oré KP, Gálvez-Valverde AA, Jiménez-Santos M, Kimura-Hayama E.   +4 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Effects of tocilizumab on renal function and oxidative stress in an experimental model of acute ischemic kidney injury. [PDF]

Rev Esc Enferm USP
Tsuchiya JM, Silva JVG, Alves MG, Silva EO, Maia AO, Vattimo MFF.   +5 more
europepmc   +1 more source

La genèse des espèces animales

L. Cuénot
semanticscholar   +1 more source

Les retouchoirs en matières dures animales : une comparaison entre Moustérien final et Uluzzien

, 2012
Camille Anne Jéquier, Matteo Romandini, ∗. MarcoPeresani, Retouchoir, Moustérien Uluzzien   +4 more
semanticscholar   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

[Dignifying what matters most: a perspective on breaking down life's hierarchies]. [PDF]

Aten Primaria
de Rivera Atienza VA, Bellido Izquierdo P.   +1 more
europepmc   +1 more source