Results 31 to 40 of about 2,912 (306)

Animals and Animality in Irish Fiction

open access: yes, 2022
This chapter charts a transhistorical narrative to analyze the evolving permutations encoded within human–animal binarisms. Maureen O’Connor argues that “The native Irish were long believed to have powers of human–animal metamorphosis.” O’Connor states that the Welsh clergyman Giraldus Cambrensis, and later Edmund Spenser in his View of the Present ...
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dimensions politiques et sociales du motif de l’animalité dans Abou Leila et Plumes

open access: yesL’Année du Maghreb
The films Abou Leila (Amin Sidi-Boumédiène, Algeria/France/Qatar, 2019) and Feathers (Omar El Zohairy, Egypt/France/Netherlands/Greece, 2021) have several features in common beyond the fact that they were shot in a period after the outbreak of the Arab ...
Nicolas Appelt
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Pojken med koskällan och tjuren på Nybacken

open access: yesTidskrift för Litteraturvetenskap, 2019
The Boy with the Cowbell & The Bull of Nybacken: A Queer Reading of Vilhelm Moberg’s The Emigrants Novels This article presents a queer reading of Vilhelm Moberg’s The Emigrants novel series (1949–1959), in which norm-breaking aspects of the text are
Oscar von Seth
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Liminal Femininity: Magical Realism and the Abject in Louise Erdrich’s Tracks

open access: yesELOPE, 2022
The article examines the liminal nature of the two central female characters in Louise Erdrich’s novel Tracks. Despite appearing as opposites, Fleur and Pauline, members of the Chippewa tribe, are both portrayed as socially abject and victims of the ...
Anja Mrak
doaj   +1 more source

The melancholic animal:On depression and animality [PDF]

open access: yes, 2019
The phenomenon of depression fundamentally challenges common western ideas about what it means to be human, such as Cartesian distinctions between body and mind, and existing notions of rationality, autonomy and agency.
Meijer, E.
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Confused Robots and Incompetent Humans in Jean-Pierre Jeunet’s Bigbug (2022)

open access: yesAlternative Francophone
Jean-Pierre Jeunet has been working on the presentation of struggling human bodies, in his films such as Delicatessen (1991), La Cité des enfants perdus/The City of Lost Children (1995), and most recently, Bigbug (2022).
Hyunjin Kim
doaj   +1 more source

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