Results 161 to 170 of about 3,106,029 (269)

Bovine Tuberculosis in a Rural Greek Area: Within-Herd Prevalence and Risk Factors in 30 Tuberculosis Skin Test-Positive Herds. [PDF]

Animals (Basel)
Tsakmakidis I, Kantzoglou T, Kyrana Z, Alvanou MV, Koutouzidou G, Melfou K, Giantsis IA.   +6 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Modeling Hemorrhagic Shock in Male SD Rats by Fixed Volume Blood Withdrawal Followed by Partial Resuscitation and Long-Term Outcome Assessment. [PDF]

Med Sci (Basel)
Ismailova AM, Palikov VA, Severyukhina MS, Tukhovskaya EA, Kholina AV, Semushina SG, Slashcheva GA, Shaykhutdiniva ER, Kravchenko IN, Kazakov VA, Kazakova EN, Kazakova MS, Timakina AB, Shinelev MV, Rykov VA, Patsap OI, Dyachenko IA, Murashev AN.   +17 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Peripheral human mAb therapy yields modulation of neuroinflammation and long-term functional recovery from lyssavirus infection. [PDF]

Emerg Microbes Infect
Huaman C, Xu Y, Lott NM, Santorella EM, Rader M, Strazzella AM, Clouse C, King JM, Melnyk M, Hong J, Yan L, Paskey AC, Luquette AE, Malagon F, Cer RZ, Bishop-Lilly KA, Perl DP, Broder CC, Xu K, Schaefer BC.   +19 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

The implementation of European animal welfare standards in Turkish animal protection legislation and case law. [PDF]

Front Vet Sci
Uyar Ç.
europepmc   +1 more source

‘Animal electricity’

Journal of Psychosomatic Obstetrics & Gynecology, 2001
openaire   +3 more sources