Results 221 to 230 of about 8,608,049 (432)

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Dynamics of gut colonization by commensal and pathogenic bacteria that attach to the intestinal epithelium. [PDF]

open access: yesNPJ Biofilms Microbiomes
Rivera DE   +9 more
europepmc   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Parasites and Parasitic Diseases in Small Animals. [PDF]

open access: yesAnimals (Basel)
García-Sánchez AM, Callejón R.
europepmc   +1 more source

Le règne animal distribué d'après son organisation,$bpour servir de base à l'histoire naturelle des animaux, et d'introduction à l'anatomie comparée,$cpar Georges Cuvier.

open access: green
Georges Cuvier   +11 more
openalex   +2 more sources

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

Global trends in antimicrobial use in food animals

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
T. V. Van Boeckel   +7 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy