Results 321 to 330 of about 9,215,153 (385)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Polyserine domains are toxic and exacerbate tau pathology in mice. [PDF]

open access: yesProc Natl Acad Sci U S A
Van Alstyne M   +3 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

GLA-3 mediates the heat shock response in Caenorhabditis elegans germ cells: A key role for the tristetraprolin (TTP) family. [PDF]

open access: yesPLoS One
Salinas LS   +6 more
europepmc   +1 more source

Author Correction: Safety evaluation of extracellular vesicles derived from hypoxia primed mesenchymal stem cells of umbilical cord and adipose tissue. [PDF]

open access: yesSci Rep
Nguyen QT   +10 more
europepmc   +1 more source

Cerebellar Purkinje cell firing reduction contributes to aging-related declining motor coordination in mice. [PDF]

open access: yesProc Natl Acad Sci U S A
Fields E   +7 more
europepmc   +1 more source

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