Results 181 to 190 of about 38,655 (248)

TARDBP (TDP‐43) Knock‐in Zebrafish Display a Late‐Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons

open access: yesAnnals of Neurology, EarlyView.
Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji   +10 more
wiley   +1 more source

From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective The growing demand for personalized treatment in multiple sclerosis (MS) highlights the need for more precise biomarkers that can outperform magnetic resonance imaging and clinical assessment in patient stratification. Advances in multiplex proteomic technologies suggest that cerebrospinal fluid (CSF) analysis at MS onset may not only improve
Laura Ghezzi   +10 more
wiley   +1 more source

Animation of echocardiographic images to create a cine loop using the animator program

open access: bronze, 1991
Daniel M. Shindler   +4 more
openalex   +1 more source

Detecting Awareness in the Intensive Care Unit Using Functional Near‐Infrared Spectroscopy

open access: yesAnnals of Neurology, EarlyView.
Objective Signs of awareness after acute severe brain injury are critical for informing goals‐of‐care decisions, ranging from the continuation of aggressive life‐sustaining therapy to comfort‐focused end‐of‐life measures. However, awareness may go undetected in some critically ill patients when assessed using bedside behavioral neurological examination.
Karnig Kazazian   +10 more
wiley   +1 more source

Endogenous Repair in Vanishing White Matter

open access: yesAnnals of Neurology, EarlyView.
Objective Vanishing white matter is a leukodystrophy with remarkable regional variation in disease severity. The cerebral and cerebellar white matter chronically degenerates, while stress‐induced episodes of rapid neurological deterioration coincide with the appearance of acute focal lesions in the deep gray structures and brainstem.
Bonnie C. Plug   +7 more
wiley   +1 more source

Design and Development of rGO and Polymer‐Based Patches for Cardiac Tissue Engineering

open access: yesJournal of Applied Polymer Science, EarlyView.
ABSTRACT Myocardial infarction (MI), caused by coronary artery blockage, is a leading cause of death worldwide and results in permanent heart damage. Current treatments have limited success in fully restoring cardiac function, leading to increased interest in tissue engineering solutions.
Israa F. Abdulazez   +7 more
wiley   +1 more source

Early synapsids neurosensory diversity revealed by CT and synchrotron scanning

open access: yesThe Anatomical Record, EarlyView.
Abstract Non‐mammaliaform synapsids (NMS) represent the closest relatives of today's mammals among the early amniotes. Exploring their brain and nervous system is key to understanding how mammals evolved. Here, using CT and Synchrotron scanning, we document for the first time three extreme cases of neurosensory and behavioral adaptations that probe ...
J. Benoit   +6 more
wiley   +1 more source

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