Results 41 to 50 of about 63,416 (295)

Pneumopéricarde compliquant un traumatisme thoraco-abdominal par coup de sabot

open access: yesThe Pan African Medical Journal, 2014
Il n'existe que peu d'études consacrées aux accidents d'équitation. Avec une incidence de 36/100000 pratiquants, et un taux de mortalité de 0.06/100000, la prévalence dans la population générale reste faible, mais la gravité de ces accidents est liée à ...
Ré da Guemmoune, Nabil Kanjaa
doaj   +1 more source

" Animal, trop animal " [PDF]

open access: yesLe Portique, 2009
Dans la tradition philosophique, on trouve plusieurs definitions de l’homme. La celebre definition aristotelicienne, zoon logon echon (animal doue du langage ou animal rationnel) fournit le paradigme ainsi que la methode de toutes les definitions successives.
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

VR Scene Detail Enhancement Method Based on Depth Reinforcement Learning Algorithm

open access: yesInternational Journal of Computational Intelligence Systems
In virtual reality, due to factors such as light sources and surface materials of objects, the details of the scene exhibit extremely complex changes, making it difficult to capture environmental modeling relationships and reducing the quality of scene ...
Changbao Feng   +3 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

3ème congrès international « animation socioculturelle » 2007

open access: yesLicere, 2007
3ème congrès international « animation socioculturelle » 2007 26 a 28 de setembro de 2007 Lucerna ...
3ème congrès international « animation socioculturelle » 2007
doaj  

Evaluation of coupled finite element/meshfree method for a robust full-scale crashworthiness simulation of railway vehicles

open access: yesAdvances in Mechanical Engineering, 2016
The crashworthiness of a railway vehicle relates to its passive safety performance. Due to mesh distortion and difficulty in controlling the hourglass energy, conventional finite element methods face great challenges in crashworthiness simulation of ...
Zhao Tang   +4 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

SSA: Smart Sugarcane Agriculture Utilizing the Zachman Framework for Advanced Enterprise Architecture [PDF]

open access: yesSHS Web of Conferences
Enterprise Architecture (EA) is now indispensable for organizations to manage their business operations, data, infrastructure, and ICT systems.
Pramono Andy   +5 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Home - About - Disclaimer - Privacy