Results 21 to 30 of about 17,913 (203)

Outcomes of Trabeculectomy and Glaucoma Drainage Device Surgery in Congenital Aniridia-Associated Glaucoma: A Systematic Review and Meta-Analysis [PDF]

Ophthalmology and Therapy
Introduction This study aimed to compare the surgical outcomes of trabeculectomy and glaucoma drainage device (GDD) implantation in patients with congenital aniridia.
Gábor Tóth, Shanhe Liu, Shuailin Li, Szilárd Váncsa, Mátyás Paczkó, Tamás Kói, Péter Hegyi, Nóra Szentmáry   +7 more
doaj   +2 more sources

Chandelier retroillumination-assisted cataract surgery in two cases of congenital aniridia with severe aniridia-associated keratopathy: case series

Therapeutic Advances in Ophthalmology
Congenital aniridia is a rare genetic eye disorder often associated with PAX6 gene mutations, leading to complex ocular manifestations, including aniridia-associated keratopathy (AAK) and cataracts.
Joseph Hu, Chao-Chien Hu
doaj   +2 more sources

Aniridia associated with congenital aphakia and secondary glaucoma

Indian Journal of Ophthalmology, 2009
We report a case of aniridia associated with congenital aphakia and secondary glaucoma. A 35-year-old male presented with aniridia, congenital aphakia and secondary glaucoma in both eyes.
Moreker Mayur, Parikh Rajul, Parikh Shefali, Thomas Ravi   +3 more
doaj   +1 more source

Effects of Aberrant Pax6 Gene Dosage on Mouse Corneal Pathophysiology and Corneal Epithelial Homeostasis [PDF]

, 2011
Background: Altered dosage of the transcription factor PAX6 causes multiple human eye pathophysiologies. PAX6(+/-) heterozygotes suffer from aniridia and aniridia-related keratopathy (ARK), a corneal deterioration that probably involves a limbal ...
Fullwood, Nigel J., Martin, Francis L., Collinson, J. Martin, Richard L Mort, Morley, Steven D., Morley Steven D., West John D., Bentley, Adam J., Adam J Bentley, Mort, Richard L, Collinson J. Martin, Panagiotis Douvaras, Collinson, J Martin, J Martin Collinson, Bentley Adam J., Mort Richard L., Martin, Francis L, Bentley, Adam J, Morley, Steven D, Martin Francis L., Douvaras, Panagiotis, Steven D Morley, Robert E Hill, Mort, Richard L., West, John D., Hill, Robert E, Fullwood, Nigel J, Nigel J Fullwood, Douvaras Panagiotis, Fullwood Nigel J., Francis L Martin, Hill Robert E., Hill, Robert E., West, John D, John D West   +34 more
core   +1 more source

Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy [PDF]

, 2019
PURPOSE. To investigate fundus autofluorescence (FAF) and other fundus manifestations in congenital aniridia. METHODS. Fourteen patients with congenital aniridia and 14 age- and sex-matched healthy controls were examined. FAF images were obtained with an
Utheim, Tor P.,, Rueegg, Corina S., Landsend, Erlend Christoffer Sommer, Pedersen, Hilde R.,, Landsend, Erlend C. S., Pedersen, Hilde Røgeberg, Pedersen, Hilde R., Utheim, Oygunn A.,, Moe, Morten C.,, Moe, Morten C., Utheim, Tor Paaske, Baraas, Rigmor C., Rueegg, Corina Silvia, Landsend, Erlend C. S.,, Lagali, Neil, Moe, Morten Carsten, Utheim, Tor P., Utheim, Oygunn A., Bragadottir, Ragnheidur,, Baraas, Rigmor C.,, Utheim, Øygunn Aass, Bragadottir, Ragnheidur, Lagali, Neil,, Rueegg, Corina S.,   +23 more
core   +1 more source

Traumatic Aniridia Following a Blunt Ocular Trauma in a Pseudophakic Patient [PDF]

, 2014
Blunt ocular traumas cause serious ocular problems in the anterior and posterior segments of the eye and even may result in globe perforation. In the literature, some cases have been reported with aniridia by traumatic iris expulsion and preserved ...
Tufan, Hasan Ali, Selçuk Kara, Gencer, Baran, Baran Gencer, Hasan Ali Tufan, Comez, Arzu Taskiran, Arzu Taşkıran Çömez, Kara, Selcuk, Arikan, Sedat, Sedat Arıkan   +9 more
core   +1 more source

A rare missense PAX6 mutation causes atypical aniridia in a three-generation Chinese family [PDF]

International Journal of Ophthalmology
AIM: To investigate the molecular diagnosis of a three-generation Chinese family affected with aniridia, and further to identify clinically a PAX6 missense mutation in members with atypical aniridia.
Zhi-Bo Lin, Chun-Yun Feng, Jin Li, An-Peng Pan, Hai-Sen Sun, A-Yong Yu, Shi-Hao Chen   +6 more
doaj   +1 more source

Novel clinical presentation and PAX6 mutation in families with congenital aniridia

Frontiers in Medicine, 2022
PurposeTo explore the clinical phenotype and genetic defects of families with congenital aniridia.MethodsFour Chinese families with aniridia were enrolled in this study. The detailed ocular presentations of the patients were recorded.
Ruru Guo, Xiaotian Zhang, Xiaotian Zhang, Aihua Liu, Jian Ji, Wei Liu   +5 more
doaj   +1 more source

New horizons in aniridia management: Clinical insights and therapeutic advances

Taiwan Journal of Ophthalmology, 2023
Congenital aniridia is a rare genetic eye disorder characterized by the complete or partial absence of the iris from birth. Various theories and animal models have been proposed to understand and explain the pathogenesis of aniridia.
Abha Gour, Shailaja Tibrewal, Aastha Garg, Mehak Vohra, Ria Ratna, Virender Singh Sangwan   +5 more
doaj   +1 more source

Congenital Aniridia: Exploring Visual Disabling Manifestations in the Ocular Surface and Ocular Fundus through Clinical and Translational Approaches

, 2020
Congenital aniridia is primarily characterized by hypoplasia of the iris and the retinal fovea. Foveal hypoplasia is the main cause of congenital reduced vision. Keratopathy is common in aniridia, leading to considerable visual impairment.
Landsend, Erlend Christoffer Sommer
core   +1 more source