Results 51 to 60 of about 25,639 (292)
Diadenosine polyphosphates in the tears of aniridia patients [PDF]
, 2015 Purpose To quantify diadenosine polyphosphate levels in tears of congenital aniridia patients to estimate the ocular surface changes associated with congenital aniridia compared to normal individuals. Methods Fifteen patients diagnosed with congenital
Carracedo Rodríguez, Juan Gonzalo +2 more
core +1 more source
Artificial iris implantation in congenital aniridia A systematic review.
Survey of ophthalmology, 2022 Congenital aniridia is a rare, panocular disorder with a main phenotypic characteristic of a partial or complete absence of the iris existing alongside other ocular morbidities such as cataract, keratopathy, optic nerve and foveal hypoplasia, and ...
Davide Romano +8 more
semanticscholar +1 more source
Iris prosthesis in traumatic aniridia as an attempt to control refractory glaucoma induced by silicone oil in the anterior chamber: case report [PDF]
, 2005 The objective of this report is to demonstrate the effectiveness of an iris prosthesis to treat a refractory glaucoma induced by silicone oil in the anterior chamber. This case is about a patient who suffered a trauma caused by firearm shrapnel.
Abib, Fernando César +4 more
core +3 more sources
Acta ophthalmologica, 2022 The purpose of this study is to study the frequency, surgical transplantation technique and outcome in patients with aniridia‐related keratopathy (ARK) with two‐year follow‐up period.
A. Viberg +4 more
semanticscholar +1 more source
Pax6- and Six3-Mediated Induction of Lens Cell Fate in Mouse and Human ES Cells [PDF]
, 2014 Embryonic stem (ES) cells provide a potentially useful in vitro model for the study of in vivo tissue differentiation. We used mouse and human ES cells to investigate whether the lens regulatory genes Pax6 and Six3 could induce lens cell fate in vitro ...
Anchan, Raymond M. +11 more
core +7 more sources
Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development [PDF]
, 2012 Molecular oxygen is essential for the development, growth and survival of multicellular organisms. Hypoxic microenvironments and oxygen gradients are generated physiologically during embryogenesis and organogenesis.
Abrahams, S. +13 more
core +1 more source
miRNA Expression Profile in Primary Limbal Epithelial Cells of Aniridia Patients
Investigative Ophthalmology and Visual SciencePurpose This study evaluates the microRNA (miRNA) expression profile in primary limbal epithelial cells (pLECs) of patients with aniridia. Methods Primary human LECs were sampled and isolated from 10 patients with aniridia and 10 healthy donors.
Mahsa Nastaranpour +8 more
semanticscholar +1 more source
Congenital Aniridia and Ocular motility.
American journal of ophthalmology-glaucoma, 2022 PURPOSE To study the frequency and types of strabismus in congenital aniridia, the presence of associated nystagmus, foveal hypoplasia, and congenital cataracts. DESIGN Prospective, single-center cohort study.
M. Alafaleq +2 more
semanticscholar +1 more source
Türk Oftalmoloji Dergisi, 2022 Congenital aniridia is a rare condition affecting a wide range of ocular structures, from the ocular surface to the retina. We present the case of a 59-year-old woman with PAX6- and WT1-negative congenital aniridia who developed aniridia-associated ...
Ioannis Athanasiadis +2 more
doaj +1 more source
Longitudinal genotype-phenotype analysis in 86 patients with PAX6-related aniridia
JCI Insight, 2021 Aniridia is most commonly caused by haploinsufficiency of the PAX6 gene, characterized by variable iris and foveal hypoplasia, nystagmus, cataracts, glaucoma, and aniridia-related keratopathy (ARK).
Vivienne Kit +3 more
semanticscholar +1 more source