Natural killer cell engagers: From bi-specific to tri-specific and tetra-specific engagers for enhanced cancer immunotherapy. [PDF]
Multi‐specific NKCEs: Multi‐specific NK cell engagers (NKCEs) enhance the immune system's ability to target and destroy tumor cells. Diverse targeting: These NKCEs can engage multiple antigens on NK cells and tumor cells, providing a more robust cytotoxic response.
Zhu A, Bai Y, Nan Y, Ju D.
europepmc +2 more sources
Natural killer cells and engagers: Powerful weapons against cancer. [PDF]
Summary Natural killer (NK) cells are innate immune effectors whose functions rely on receptors binding cytokines, recognizing self‐molecules, or detecting danger signals expressed by virus‐infected or tumor cells. The potent cytotoxic potential makes NK cells promising candidates for cancer immunotherapy.
Bottino C +3 more
europepmc +2 more sources
Fifty Years of Natural Killer Cells: Milestones and Future Horizons. [PDF]
To mark 50 years of NK cell research, a 2025 Karolinska symposium traced discoveries from spontaneous cytotoxicity and “missing self” recognition to receptor biology, cellular diversity, and translational advances, highlighting NK cells’ evolution into modern immunotherapy.
Lundqvist A +7 more
europepmc +2 more sources
The Power of Three: Nanomaterials for Natural Killer (NK) Cell Immunoengineering Maximize Their Potency if They Exploit Multireceptor Stimulation. [PDF]
Graphene oxide nanoflakes (NGO) are here used as scaffolds to create nanoclusters of monoclonal antibodies (mAb) that activate natural killer (NK) cells. The most potent activation is delivered by multifunctional NGO‐mAb that stimulate three activating receptors simultaneously.
Dodd H, Guerra N, Dunlop IE.
europepmc +2 more sources
Comparative multi-index analysis of existing drought typology and environmental droughts in a climate-stressed region [PDF]
Climate change is amplifying drought impacts globally, yet conventional drought typology (meteorological, agricultural, hydrological) systematically excludes environmental drought, a critical driver of ecosystem collapse, from multi-index comparative ...
Aman Srivastava +2 more
doaj +2 more sources
ANKET ÇALIŞMASININ DÜŞÜNDÜRDÜKLERİ
Atilla Soran, A.Veysel Polat
doaj +1 more source
Evaluation of Dental Trauma Knowledge Levels of Cyclists in Turkiye
Background: Cycling is a risky sport in terms of dental injury. Immediate treatment of traumatized teeth is very critical for the prognosis. This study aims to evaluate the knowledge levels and attitudes of cyclists in Turkey about dental trauma and its ...
Fatma Tunç, Emre Çulha
doaj +1 more source
THE MOVEMENT IMAGERY QUESTIONNAIRE-3: RELIABILITY AND VALIDITY STUDY ON TURKISH SAMPLE
The aim of the present study was to test the reliability and validity of the Movement Imagery Questionnaire-3 (MIQ-3) (Williams et al., 2012) among a Turkish sample. The study was conducted with 136 (104 women, 32 men) university students.
Hamit Coşkun +2 more
doaj +1 more source
The plant epitranscriptome: revisiting pseudouridine and 2′‐O‐methyl RNA modifications
Fine‐tuning of RNA modifications has recently been proposed to improve crop production, and these post‐transcriptional RNA modifications have been shown to be highly dynamic. In this review, we summarize recent findings on available technologies for mapping pseudouridine and 2′‐O‐methyl groups and their functional significance. Summary There is growing
Muthusamy Ramakrishnan +9 more
wiley +1 more source
Abstract The domestication of pigeonpea has severely impacted the intrinsic host‐plant resistance (HPR) to pest and diseases, particularly pod borer (Helicoverpa armigera hubner). This study with 41 Australian wild Cajanus genotypes and interspecific hybrids demonstrated a high level of resistance to H. armigera in the accessions of Cajanus acutifolius,
Prameela Vanambathina +5 more
wiley +1 more source

