Results 111 to 120 of about 557,732 (322)

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

Advanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang, Yuanyi Hua, Xin Wen, Zhumei Liao, Jianheng Ren, Yajun Weng, Qin Wang   +6 more
wiley   +1 more source

Cuboid fracture: surgical treatment, midterm follow-up, and management algorithm

Journal of the Foot & Ankle
Objectives: Describe the epidemiology of cuboid fracture, the mechanisms of injury and associated injuries, the progression to osteoarthritis, and propose a surgical management algorithm.
Fernando Vargas, Leonardo Lagos Sepulveda, Mauricio Parra Henriquez, Christian Urbina Bahamonde, Francisco Bravo Gallardo, Christian Bastias Soto   +5 more
doaj   +1 more source

Origin of the ankle in the ultrahigh energy cosmic ray spectrum, and of the extragalactic protons below it [PDF]

, 2015
M. Unger, Glennys R. Farrar, Luis A. Anchordoqui   +2 more
openalex   +1 more source

Low Regional Homogeneity of Intrinsic Cerebellar Activity in Ankle Instability: An Externally Validated rs-fMRI Study

, 2022
Xiao’ao Xue, Rong Lü, Di Zang, Hong Li, Hui Zhang, Hanlin Xu, Qianru Li, Tengjia Ma, Weijun Tang, SHUANG CHEN, HE WANG, Yinghui Hua   +11 more
openalex   +1 more source

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong, Penghao Ji, Jinxi An, Junchao Huang, Ziheng Bu, Xudong Zhang, Wei Liu, Tingyu Wu, Sen Wang, Wei Zhu, Yuhui Li, Jixian Wan, Sudan Xu, Minfeng Huo, Peng Wu   +14 more
wiley   +1 more source

Radiological characteristics and injury mechanism of Logsplitter injury: a descriptive and retrospective study

BMC Musculoskeletal Disorders
Background Logsplitter Injury is a type of high-energy ankle fracture dislocation. The mechanism of injury has not been described in detail. A detailed understanding of the radiological features and pathological changes can further guide treatment ...
Jing-Qi Liang, Yan Zhang, Yang Yue, Hui Feng, Pei-Long Liu, Xiao-Jun Liang, Hong-Mou Zhao   +6 more
doaj   +1 more source

Active controlled motion in early rehabilitation improves outcome after ankle fractures: a randomized controlled trial [PDF]

, 2017
Hendrik Jansen, Martin C. Jordan, Sönke P. Frey, Stefanie Hölscher-Doht, Rainer H. Meffert, Timo M. Heintel   +5 more
openalex   +1 more source

Cardio-ankle vascular index is useful screening method to detect obstructive coronary artery disease in asymptomatic diabetes patients with subclinical atherosclerosis [PDF]

, 2021
Teruo Ono, Toru Miyoshi, Y Ueki, Kosuke Kuroda, Eisuke Saito, Masahiko Tsuji, Kentaro Kawamura, Koji Tokioka, Tohru Ohe, Yusuke Kawai   +9 more
openalex   +1 more source

Soft Magnetic Sensor Array for Amphibious Measurement of 3D Muscle Deformation Distribution for Human Motion Recognition

Advanced Intelligent Systems, EarlyView.
This article develops a soft magnetic sensor array to extract 3D and distributional muscle deformations, which has highly consistent measurements in amphibious environments, robustness to hydraulic pressure, and about 200 ms faster response than an inertial measurement unit, achieving over 98% classification accuracy and below 3% phase estimation ...
Yuchao Liu, Zihan Chen, Chuxuan Guo, Zijie Liu, Yibin Chen, Xuan Wu, Zhuo Li, Qining Wang, Jiajie Guo   +8 more
wiley   +1 more source

Individual USH2 proteins make distinct contributions to the ankle link complex during development of the mouse cochlear stereociliary bundle [PDF]

, 2015
Junhuang Zou, Pranav Dinesh Mathur, Tihua Zheng, Yong Wang, Ali A. Almishaal, Albert H. Park, Jun Yang   +6 more
openalex   +1 more source