Objective Synovial fibroblasts directly contribute to inflammation and damage in immune‐mediated inflammatory arthritis. CD248/Endosialin is expressed by fibroblasts in the synovium, is highly upregulated during inflammation and has been proposed as a potential therapeutic target.
Samuel Kemble +12 more
wiley +1 more source
Ankle Sprains in Athletes: Current Epidemiological, Clinical and Imaging Trends
Pia M Jungmann,1,2 Thomas Lange,3 Markus Wenning,4 Frédéric A Baumann,5 Fabian Bamberg,1 Matthias Jung1 1Department of Diagnostic and Interventional Radiology, Medical Center–University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg ...
Jungmann PM +5 more
doaj
Modelling treatment, age- and gender-specific recovery in acute injury studies [PDF]
Background: Acute injury studies often measure physical ability repeatedly over time through scores that have a finite range. This can result in a faster score change at the beginning of the study than towards the end, motivating the investigation of ...
Lamb, S. E. (Sallie E.) +2 more
core
Ankle injury management (AIM) : design of a pragmatic multi-centre equivalence randomised controlled trial comparing close contact casting (CCC) to open surgical reduction and internal fixation (ORIF) in the treatment of unstable ankle fractures in patients over 60 years [PDF]
Background: Ankle fractures account for 9% of all fractures with a quarter of these occurring in adults over 60 years. The short term disability and long-term consequences of this injury can be considerable.
David J Keene +39 more
core +2 more sources
MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice
Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez +13 more
wiley +1 more source
Dissecting the dissection laboratory: Elements for designing a human anatomy laboratory
Abstract The human anatomy dissection laboratory is a critical component of anatomical and medical education. Development, maintenance, and stocking of these laboratory spaces have unique demands, with all of the challenges in running a laboratory with Biosafety Laboratory Level 2 (BSL‐2) classification, housing a large volume of tissues saturated with
Rhiannon E. Robinson +13 more
wiley +1 more source
Abstract In recent years, arthroscopic anterior talofibular ligament (ATFL) repair techniques have been increasingly used in the treatment of chronic ankle instability. Arthroscopic approaches not only allow for the management of concomitant intra‐articular pathologies but also help minimize wound‐related complications associated with open surgery and ...
Semih Yaş +5 more
wiley +1 more source
Sports Injuries in Basketball Players: A Systematic Review
(1) Background: The objective of this systematic review was to collect relevant data in the available contemporary studies about sports injuries of basketball players and explain differences in sports injuries relative to gender, location, sport, and ...
Nikola Aksović +12 more
doaj +1 more source
Abstract A constricted retrofibular fibro‐osseous tunnel is the cause of intrasheath peroneal tendon subluxation. If it is because of a combination of an abnormal convex or flat retrofibular groove and the presence of a space‐occupying low‐lying muscle belly, endoscopic groove deepening and resection of a low‐lying muscle is a reasonable surgical ...
Xiaohua Pan +6 more
wiley +1 more source
Peroneus Longus Autograft Harvest and Preparation for Anterior Cruciate Ligament Reconstruction
Abstract The peroneus longus tendon (PLT) has emerged as a promising autograft option for anterior cruciate ligament reconstruction because of its favorable biomechanical properties, consistent graft diameter, and minimal donor‐site morbidity; however, detailed descriptions of graft harvesting and preparation techniques remain limited within literature.
Mathew Park +4 more
wiley +1 more source

