Results 231 to 240 of about 2,333,211 (333)

A comparison of medical encounters of older and younger athletes participating at major games [PDF]

, 2019
Brown, Mark, Constantinou, Maria, Reaburn, Peter R J   +2 more
core  

Factors Influencing Sport‐Induced Bleeding in Patients With Haemophilia Without Inhibitors: A Single Centre Retrospective Study of People Born in the 2000s

Haemophilia, EarlyView.
ABSTRACT Introduction Recent advances in prophylaxis with clotting factor concentrates have enabled people with haemophilia (PwH) to participate in high‐intensity exercises; however, this does not preclude them from sports‐induced bleeding (SIB). Aim To investigate factors influencing the recent occurrence of SIB among PwH.
Rie Shirayama, Takuma Ito, Tetsuji Sato, Takayuki Hoshina   +3 more
wiley   +1 more source

Evidence-based clinical practice guidelines for the management of acute ankle injuries according to: a PRISMA systematic review and quality appraisal with AGREE II. [PDF]

BMC Musculoskelet Disord
Bsoul N, Ning L, Cai L, Mazmanyan D, Porter D.   +4 more
europepmc   +1 more source

Final Analysis of the Phase 1/2 Trial of Valoctocogene Roxaparvovec for Severe Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Valoctocogene roxaparvovec is an adeno‐associated virus vector serotype 5 (AAV5)‐mediated gene therapy for severe haemophilia A (HA). Aim Report the final safety and efficacy results of the phase 1/2 trial of valoctocogene roxaparvovec. Methods An open‐label phase 1/2 trial (NCT02576795) enrolled adult males with severe HA (factor
Priyanka Raheja, Savita Rangarajan, Will Lester, Bella Madan, Glenn F. Pierce, Emily Symington, Carolyn Millar, Dane Osmond, Mingjin Li, Konstantia‐Maria Chavele   +9 more
wiley   +1 more source

Gait Pattern at Different Speeds in Persons With Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Persons with haemophilia (PwH) have a risk of bleeding in joints, especially in elbow, knee and ankle. In the long term, this leads to haemophilic arthropathy (HA), which results in joint deformities. Aim This study aims to examine how walking speed and HA affect (1) foot pressure distribution, (2) average vertical peak pressure ...
Marius Brühl, Pia Möllers, Jamil Hmida, Fabian Tomschi, Georg Goldmann, Frank A. Schildberg, Johannes Oldenburg, Andreas C. Strauss, Thomas Hilberg   +8 more
wiley   +1 more source

Investigator‐Led Research to Improve the Diagnostic Assessment of Platelet Function Disorders: Reflections on the Challenges and Rewards

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Investigator‐led research and quality improvement initiatives have led to important improvements in the diagnostic assessment of platelet function disorders (PFD). Methods Personal reflections were used to summarize our contributions to knowledge on PFD diagnostic assessment, pathogenesis, and bleeding risks.
Catherine P. M. Hayward
wiley   +1 more source

AI‐enhanced decision support for fall patients: streamlining inpatient flow in the emergency department

International Transactions in Operational Research, EarlyView.
Abstract Emergency department (ED) overcrowding and inefficient patient flow are significant operational challenges, often amplified by the volume of patients sustaining fall‐related injuries. This study predicts hospital admission for these encounters by leveraging unstructured clinical text: triage chief complaints (reasons for seeking care) and ...
Dinesh R. Pai, Usha Ananthakumar, Shruti Sureshan   +2 more
wiley   +1 more source

Diabetic foot ulcer‐related amputation is associated with twofold increased risk of cardiovascular disease: A Korean National Health Information Database Study

Journal of Diabetes Investigation, EarlyView.
Data/Design: Nationwide, population‐based longitudinal cohort using the Korean National Health Insurance Service health checkup database (index 2009–2012) with follow‐up through December 31, 2018. Population/Exposure: Adults with diabetes (N = 1,229,689); DFU‐related amputation at baseline (n = 1,486) vs no DFU‐related amputation.
Jinsun Jang, Bong‐Seong Kim, Hye Won Yang, Heejun Son, Dong Yeon Lee, Min Gyu Kyung, Hwan Jun Jae, Saebeom Hur, Sang Wha Kim, Sanghyun Ahn, Kyung‐Do Han, Soo Heon Kwak   +11 more
wiley   +1 more source

Variation in trabecular bone microarchitecture across rhesus macaque (Macaca mulatta) load‐bearing joints

Journal of Anatomy, EarlyView.
Aging of bone density (BV/TV) is regional: Forelimb [left] elements gain bone sporadically (orange) but hind limb elements [right] lose bone globally (blue). Abstract Globally, human population structure is quickly trending older, increasing the prevalence and systemic burden of age‐related skeletal disorders such as osteoporosis.
Cassandra M. Turcotte, Aditi Raghunath, Timothy M. Ryan, Lily J. D. DeMars, Erin Siracusa, Sam K. Patterson, Cayo Biobank Research Unit, Michael L. Platt, Lauren J. N. Brent, Noah Snyder‐Mackler, Samuel E. Bauman, Michael J. Montague, Melween I. Martinez, Scott A. Williams, Susan C. Antón, James P. Higham, Sharon Kuo   +16 more
wiley   +1 more source

MRI‐based, 3D analysis of Achilles tendon longitudinal strain under passive loading reveals limitations in conventional 2D measurement

Journal of Anatomy, EarlyView.
Graphical overview of 2D and 3D length measurements of the free Achilles tendon. The figure also illustrates how the typical distal morphology of the soleus muscle affects 2D measurement. Abstract Quantifying strain in the free Achilles tendon (ATF) is essential for understanding its mechanical function, yet existing in vivo studies report inconsistent
Dongyu Deng, Hiroto Shiotani, Yasuo Kawakami   +2 more
wiley   +1 more source