Results 61 to 70 of about 102,671 (260)

Ankle joint traumas rehabilitation methods

BIO Web of Conferences, 2020
Traumas of ankle joint are the most common. Ankle injuries account for 20 to 30% of all traumas of the human locomotor system. During the life process, the ankle is subjected to sufficiently heavy loads, therefore joint injuries often occur.
Skitnevsky Vitaly, Grigoryeva Elena, Sedov Ivan, Krasilnikova Yulia, Balashova Valentina   +4 more
doaj   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

Advanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang, Yingying Wang, Lujie Yu, Chunmei Jiang, Haoyu Liu, Yaohua Chen, Shutong Wu, Qin Liu, Lingling Wei, Xiaochun Zheng, Huifang Hao, Mengting Gao, Weiwei Kang, Rong Dai, Ziliang Zheng, Ruiping Zhang   +15 more
wiley   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Ankle joint pushing mechanism by stabilization of ankle position using a brace structure

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
In the present study, a human ankle joint pushing mechanism with a brace structure was developed, and the force balance relationship of the proposed system to avoid pain at sites other than the ankle joint was evaluated.
Hideki TODA, Takeshi MATSUMOTO, Ryota TANIZAKI, Takehiro IMAEDA   +3 more
doaj   +1 more source

Mechanical Intelligence in Bone Regeneration: Bridging Material and Cellular Memory for Enhanced Healing

Advanced Science, EarlyView.
Mechanical intelligence reframes bone regeneration as a time‐dependent coupling between material and cellular memory. Biomaterials store and release mechanical history, while cells retain prior cues and remodel the repair niche. Matching these memories to healing stages may guide stage‐specific scaffolds, sensing‐assisted prediction, mechanical dosing,
Jin Tian, Guoyou Huang, Yang Chen, Teng Ma, Bo Cheng, Feng Xu, XiaoKang Li, Pei Yang, Ting Wen   +8 more
wiley   +1 more source

Simvastatin and Moxifloxacin Co-Delivery via ZIF-8/PDA Coating on PEEK Implants: A Strategy for Combating Implant-Associated Infection and Enhancing Osseointegration

International Journal of Nanomedicine
Zidong Wu,1,* Kai Ma,1,2,* Zixuan Wu,1,* Xiaoyu Guo,1 Yuning Qu,1 Zheyue Zhu,1 Weidong Zhu,1,3 Chengxin Li,2 Yi Liu,1,2 Rui Ma,1 Pei Yang1 1Joint and Foot & Ankle Ward of Orthopedic Center, The Second Affiliated Hospital of Xi’
Wu Z, Ma K, Wu Z, Guo X, Qu Y, Zhu Z, Zhu W, Li C, Liu Y, Ma R, Yang P   +10 more
doaj  

Design and Implementation of Bionic Ankle Joint and its Cable Drive Mechanism

Jixie chuandong, 2016
A bionic device for the ankle,which has shaft non-perpendicular is designed in according to the structure characteristics of human physiological ankle.
Qian Lei, Li Yihao, Wang Caidong, Chen Lumin, Wang Xinjie   +4 more
doaj  

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Human in vivo talocrural contributions to ankle joint complex kinematics during walking, running, and hopping

Heliyon
The human ankle joint complex, consisting of calcaneus, talus, and tibia, is often simplified as a single functional ankle joint, neglecting the motion of the talus.
Anja-Verena Behling, Lauren Welte, Michael J. Rainbow, Luke Kelly   +3 more
doaj   +1 more source

Changes in the Ankle Joint and Hindfoot Alignment Following Varus Deformity Correction of the Knee with Total Knee Arthroplasty

Foot & Ankle Orthopaedics, 2017
Category: Ankle, Hindfoot Introduction/Purpose: Compensatory changes occur in the ankle joint and the subtalar joint of the hindfoot to maintain neutral alignment in coronal plane when varus or valgus deformity is present in the knee joint.
Bi O Jeong MD, PhD, Jong Hun Baek MD, Wookjae Song MD   +2 more
doaj   +1 more source