Results 51 to 60 of about 118,558 (284)

Juvenile ankylosing spondylitis [PDF]

open access: yesArthritis & Rheumatism, 1971
AbstractFifteen patients with juvenile ankylosing spondylitis were reviewed. Eight presented with extraspinal arthritis. Certain clinical features were of value early in the disease in distinguishing these patients from those with juvenile rheumatoid arthritis: male sex, remittent oligoarthritis, late onset in childhood, relative sparing of hands and ...
Ladd, John R.   +2 more
openaire   +3 more sources

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

Secukinumab: A Review in Ankylosing Spondylitis

open access: yesDrugs, 2019
Secukinumab (Cosentyx®), a first-in-class fully human monoclonal antibody against interleukin-17A, is approved in several countries, including the USA and those of the EU, for the treatment of ankylosing spondylitis (AS).
Hannah A. Blair
semanticscholar   +1 more source

Biofabrication of Endothelialized, Intrinsically Vascularized 3D‐Printed Recombinant Spider Silk Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold   +9 more
wiley   +1 more source

Radiomics-based machine learning model to phenotype hip involvement in ankylosing spondylitis: a pilot study

open access: yesFrontiers in Immunology
ObjectivesHip involvement is an important reason of disability in patients with ankylosing spondylitis (AS). Unveiling the potential phenotype of hip involvement in AS remains an unmet need to understand its biological mechanisms and improve clinical ...
Zhengyuan Hu   +11 more
doaj   +1 more source

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

open access: yesAdvanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao   +18 more
wiley   +1 more source

Anaesthesia Management in a Patient With Ankylosing Spondylitis for Emergency Caesarean Section

open access: yesJournal of Obstetric Anaesthesia and Critical Care
A 34-year-old second gravida at 38 weeks presented with decreased fetal movement and was planned for emergency cesarean section for a poor Bishop’s score. She had pre-eclampsia and hypothyroidism, for which she was on medications for one week.
Chanchal Nigam   +2 more
doaj   +1 more source

Microbiota and chronic inflammatory arthritis. an interwoven link [PDF]

open access: yes, 2016
Background: Only recently, the scientific community gained insights on the importance of the intestinal resident flora for the host's health and disease.
D'Amelio, Raffaele   +3 more
core   +2 more sources

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

open access: yesAdvanced Science, EarlyView.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin   +13 more
wiley   +1 more source

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