Results 51 to 60 of about 27,612 (272)
Advanced Science, EarlyView.This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao +16 more
wiley +1 more source
A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosis
Australasian Orthodontic Journal, 2014 Introduction: Previous studies have found ankylosis occurs as a part of the inflammatory process of aseptic root resorption initiated in a rat model.1 The physiologic mechanisms behind the development of dentoalveolar ankylosis and healing response are ...
Curl Linda +3 more
doaj +1 more source
Frontiers in Pediatrics, 2023 ObjectiveTo review the radiographic manifestation and clinical appearance of children with congenital radioulnar synostosis (CRUS) retrospectively.Study designRetrospective cohort study of children with CRUS from multiple medical centers.ResultsA total ...
Pan Hong +6 more
doaj +1 more source
Advanced Science, EarlyView.This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo +10 more
wiley +1 more source
Posttraumatic hemarthrosis in view of the inflammation theory
Гений oртопедии, 2023 Introduction Post-traumatic hemarthrosis is identified as intra-articular hemorrhage accompanied by five classic signs of inflammation: hyperemia, hyperthermia, edema, pain and changes in the joint function.
Olga V. Berdiugina +2 more
doaj +1 more source
Temporomandibular Joint Gap Arthroplasty in Cats
Frontiers in Veterinary Science, 2020 Temporomandibular joint (TMJ) ankylosis is defined as fibrous or bony fusion of the mandibular head of the condylar process and the mandibular fossa of the squamous part of the temporal bone. Ankylosis of the TMJ may be intraarticular, extraarticular, or
Armeti Aghashani +2 more
doaj +1 more source
Progress in spondylarthritis. Mechanisms of new bone formation in spondyloarthritis [PDF]
, 2009 Targeted therapies that neutralize tumour necrosis factor are often able to control the signs and symptoms of spondyloarthritis. However, recent animal model data and clinical observations indicate that control of inflammation may not be sufficient to ...
de Vlam, Kurt +2 more
core +3 more sources
Functional Synovium‐Based 3D Models in the Context of Human Disease and Inflammation
Advanced NanoBiomed Research, EarlyView.The synovium is key to joint function but is often affected by diseases like rheumatoid arthritis. Finding better treatments is challenging because current lab models do not fully mimic real tissues. New 3D technologies, like bioprinting, offer better methods to study these diseases, improve drug testing, and develop personalized treatments, bringing ...
Amelia Heslington +3 more
wiley +1 more source
Reassessment of Xenodens calminechari with a discussion of tooth morphology in mosasaurs
The Anatomical Record, EarlyView.Abstract Xenodens calminechari is a mosasaurid taxon named by Longrich et al. (2021) based on the holotype MHNM.KH.331, a left maxilla with several teeth. This holotype was obtained nonscientifically (without technical supervision) from an area in Morocco that yields many manipulated or forged specimens. Examination of Longrich et al.
Henry S. Sharpe +2 more
wiley +1 more source