Results 31 to 40 of about 258,567 (178)

Paternal Occupational Exposure to Endocrine‐Disrupting Chemicals as a Risk Factor for Leukaemia in Children: A Case‐Control Study from the North of England

Advances in Epidemiology, Volume 2014, Issue 1, 2014., 2014
Occupations with exposures to a variety of chemicals, including those thought to be potential endocrine disruptors, have been associated with an increased risk of leukaemia in offspring. We investigated whether an association exists between paternal occupations at birth involving such exposures and risk of leukaemia in offspring.
Mark S. Pearce, Lucy R. Baxter, Louise Parker, Peter N. Lee   +3 more
wiley   +1 more source

LC‐MS/MS Identification of a Bromelain Peptide Biomarker from Ananas comosus Merr

Evidence-Based Complementary and Alternative Medicine, Volume 2012, Issue 1, 2012., 2012
Bromelain (Br) is a cysteine peptidase (GenBank AEH26024.1) from pineapple, with over 40 years of clinical use. The constituents mediating its anti‐inflammatory activity are not thoroughly characterized and no peptide biomarker exists. Our objective is to characterize Br raw material and identify peptides in the plasma of Br treated mice.
Eric R. Secor Jr., Steven M. Szczepanek, Anurag Singh, Linda Guernsey, Prabitha Natarajan, Karim Rezaul, David K. Han, Roger S. Thrall, Lawrence K. Silbart, Vassya Bankova   +9 more
wiley   +1 more source

Frequency analysis of HLA class I alleles in Iranian patients with progressive and non-progressive chronic lymphocytic leukemia [PDF]

, 2013
Chronic lymphocytic leukemia (CLL) is a malignant disorder of B cell origin, with low incidence in Asian populations. In this study we investigated the HLA-class I A and B allele frequencies in 87 Iranian CLL patients and 64 healthy controls using ...
Hojjat-Farsangi, Mohammad, Razavi, Seyed Mohsen, Sharifian, Ramazan Ali, Shokri, Fazel   +3 more
core   +1 more source

A One Health approach to overcoming fungal disease and antifungal resistance.

WIREs Mechanisms of Disease, 2023
The global burden of fungal disease poses a substantial threat to human, animal, and environmental health, endangering both human and livestock populations and creating vulnerabilities to food supplies world-wide.
M. Woods, J. A. McAlister, J. Geddes-McAlister   +2 more
semanticscholar   +1 more source

Bayesian Analysis of a Lipid‐Based Physiologically Based Toxicokinetic Model for a Mixture of PCBs in Rats

Journal of Toxicology, Volume 2012, Issue 1, 2012., 2012
A lipid‐based physiologically based toxicokinetic (PBTK) model has been developed for a mixture of six polychlorinated biphenyls (PCBs) in rats. The aim of this study was to apply population Bayesian analysis to a lipid PBTK model, while incorporating an internal exposure‐response model linking enzyme induction and metabolic rate.
Alan F. Sasso, Panos G. Georgopoulos, Sastry S. Isukapalli, Kannan Krishnan, Jane C. Caldwell   +4 more
wiley   +1 more source

Outcomes in Guideline‐Based Class I Indication Versus Earlier Referral for Surgical Myectomy in Hypertrophic Obstructive Cardiomyopathy

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background In patients with obstructive hypertrophic cardiomyopathy, surgical myectomy (SM) is indicated for severe symptoms. We sought to compare long‐term outcomes of patients with obstructive hypertrophic cardiomyopathy where SM was based on guideline‐
A. Alashi, N. Smedira, K. Hodges, Z. Popović, M. Thamilarasan, P. Wierup, H. Lever, M. Desai   +7 more
semanticscholar   +1 more source

Global Burden of Atrial Fibrillation and Flutter by National Income: Results From the Global Burden of Disease 2019 Database

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2023
Background Atrial fibrillation (AF) and atrial flutter (AFL) are common conditions that can lead to significant morbidity and death. We aimed to understand the distribution and disparities of the global burden of AF/AFL as well as the underlying risk ...
A. Ohlrogge, Jan Brederecke, R. Schnabel
semanticscholar   +1 more source

Characterization of Plasminogen Binding to NB4 Promyelocytic Cells Using Monoclonal Antibodies against Receptor‐Induced Binding Sites in Cell‐Bound Plasminogen

BioMed Research International, Volume 2012, Issue 1, 2012., 2012
The NB4 promyelocytic cell line exhibits many of the characteristics of acute promyelocytic leukemia blast cells, including the translocation (15 : 17) that fuses the PML gene on chromosome 15 to the RARα gene on chromosome 17. These cells have a very high fibrinolytic capacity.
Mercè Jardí, Pere Fàbregas, María Sagarra-Tió, María José Pérez-Lucena, Jordi Félez, Lindsey A. Miles   +5 more
wiley   +1 more source

Analysis of histological frequency and pediatric cancer in Rondônia, Western Amazonia (Brazil) [PDF]

, 2018
Objective:Describe the histological and cancer frequency in children and adolescents attended at the Hospital de Base Dr. Ary Pinheiro and the Hospital de Barretos / Rondônia, Western Amazonia, in the years 2014 and 2015.
Aguiar, R. R. (Rodrigo), Almeida, F. M. (Fabrício), Paraguassú-Chaves, C. A. (Carlos), Romanholo, R. A. (Rafael), Souza, L. P. (Laurindo)   +4 more
core  

Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2024 Update

Journal of Parkinson's Disease
Background: For the past five years, our annual reports have been tracking the clinical development of new drug-based therapies for the neurodegenerative condition of Parkinson’s disease (PD). These reviews have followed the progress both of “symptomatic
K. McFarthing, Sue Buff, Gary Rafaloff, Kenneth R. Pitzer, B. Fiske, Anaya Navangul, Katelyn Beissert, Aleksandra Pilcicka, Rosie Fuest, Richard K. Wyse, S. Stott   +10 more
semanticscholar   +1 more source