Results 41 to 50 of about 258,567 (178)

USP14 governs CYP2E1 to promote nonalcoholic fatty liver disease through deubiquitination and stabilization of HSP90AA1

Cell Death and Disease, 2023
Nonalcoholic fatty liver disease (NAFLD) begins with excessive triglyceride accumulation in the liver, and overly severe hepatic steatosis progresses to nonalcoholic steatohepatitis (NASH), which is characterized by lipid peroxidation, inflammation, and ...
Dongqin Wei, Xin Tian, Longbo Zhu, Han Wang, Chao Sun   +4 more
semanticscholar   +1 more source

Washington University Magazine and Alumni News, Spring 2000 [PDF]

, 2000
https://digitalcommons.wustl.edu/ad_wumag/1150/thumbnail ...

core   +1 more source

Opiate Modulation of Gastrointestinal Motility and the Actions of Trimebutine

Canadian Journal of Gastroenterology and Hepatology, Volume 5, Issue 5, Page 185-193, 1991., 1991
Trimebutine is an opiate ligand that interacts with the μ, σ and κ receptor subclasses with approximately equal affinity. Since opiate receptors are widely distributed in the gut, and because opiate receptor subtypes may be involved in excitatory or inhibitory control mechanisms, trimebutine has an unusual profile of action that cannot be predicted on ...
Stephen M Collins, Edwin E Daniel
wiley   +1 more source

Evaluating Causal Effects of Gut Microbiome on Alzheimer’s Disease

The journal of prevention of Alzheimer's disease
The preceding evidence indicates a close correlation between imbalances in the gut microbiome and Alzheimer’s disease (AD), yet the direct causal relationship remains unclear. Our objective is to investigate this potential causal connection.
Q. Zhao, A. Baranova, H. Cao, Fuquan Zhang   +3 more
semanticscholar   +1 more source

Large‐Scale Metabolomics and the Incidence of Cardiovascular Disease

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2023
Background The study aimed to show the relationship between a large number of circulating metabolites and subsequent cardiovascular disease (CVD) and subclinical markers of CVD in the general population.
L. Lind, T. Fall, J. Ärnlöv, S. Elmståhl, J. Sundström   +4 more
semanticscholar   +1 more source

Barriers, facilitators, and other factors associated with health behaviors in childhood, adolescent, and young adult cancer survivors: A systematic review

Cancer Medicine, Volume 13, Issue 12, June 2024.
Abstract Background Healthy behaviors are paramount in preventing long‐term adverse health outcomes in childhood, adolescent, and young adult (CAYA) cancer survivors. We systematically reviewed and synthesized existing literature on barriers, facilitators, and other factors associated with health behaviors in this population.
Ismay A. E. de Beijer, Eline Bouwman, Renée L. Mulder, Philippa Steensma, Morven C. Brown, Vera Araújo‐Soares, Magdalena Balcerek, Edit Bardi, Jeanette Falck Winther, Line Elmerdahl Frederiksen, Marloes van Gorp, Sara Oberti, Rebecca J. van Kalsbeek, Tomas Kepak, Katerina Kepakova, Hannah Gsell, Anita Kienesberger, Raphaële van Litsenburg, Luzius Mader, Gisela Michel, Monica Muraca, Selina R. van den Oever, Helena J. H. van der Pal, Katharina Roser, Roderick Skinner, Iridi Stolman, Anne Uyttebroeck, Leontien C. M. Kremer, Jacqueline Loonen, Elvira C. van Dalen, Saskia M. F. Pluijm, the PanCareFollowUp Consortium, Leontien C. M. Kremer, Helena J. H. van der Pal, Renée L. Mulder, Saskia M. F. Pluijm, Rebecca J. van Kalsbeek, Selina R. van den Oever, Lars Hjorth, Cecilia Follin, Lill Eriksson, Thomas Relander, Jacob Engellau, Karin Fjordén, Karolina Bogefors, Anna S. Holmqvist, Riccardo Haupt, Monica Muraca, Brigitte Nicolas, Francesca Bagnasco, Marina Benvenuto, Anna Aulicino, Luca Laudisi, Vera Araújo‐Soares, Tomas Kepak, Katerina Kepakova, Hana Hrstkova, Viera Bajciova, Marta Holikova, Lucie Strublova, Anne Uyttebroeck, Marleen Renard, Sandra Jacobs, Heidi Segers, Monique van Helvoirt, Jeanette F. Winther, Luzius Mader, Line E. Frederiksen, Elisabeth A. W. Andersen, Gisela Michel, Stefan Boes, Katharina Roser, Jacqueline Loonen, Rosella Hermens, Irene Göttgens, Eline Bouwman, Iridi Stollman, Adriaan Penson, Dionne Breij, Roderick Skinner, Morven C. Brown, Samira Essiaf, Anne Blondeel, William Sciberras, Joke Korevaar, Mieke Rijken, Anita Kienesberger, Jaap den Hartogh, Hannah Gsell, Carina Schneider, Edit Bardi, Jeroen te Dorsthorst   +91 more
wiley   +1 more source

Overview of Inflammatory Bowel Disease Pathogenesis

Canadian Journal of Gastroenterology and Hepatology, Volume 4, Issue 7, Page 309-316, 1990., 1990
Inflammatory bowel disease (IBD) represents a difficult and challenging condition for patients, clinicians and basic investigators alike. Its etiology and pathogenesis are still unclear in spite of extensive investigations that have yielded a wealth of clinical.
C Fiocchi
wiley   +1 more source

Superiority of anthracycline‐free treatment in standard‐risk acute promyelocytic leukemia: A systematic review and comparative epidemiological analysis

Cancer Reports, Volume 7, Issue 3, March 2024.
Abstract Background Recent advances in the treatment of acute promyelocytic leukemia (APML) have seen unprecedented improvements in patient outcomes. However, such rapid growth in understanding often leads to uncertainty regarding superiority among candidate treatment regimens, especially when further scrutinized from an epidemiological perspective ...
Kane Langdon, Stevie Cosentino, Olivia Wawryk   +2 more
wiley   +1 more source

The design of simulation languages for systems with multiple modularities [PDF]

, 1990
Cover title.Includes bibliographical references (p. 11-12).Research was supported by the Army Research Office. ARO-DAAL03-86-K-0171 Research was supported by the National Science Foundation. NSF ECS-8809746by S.

core  

Impact of Chronic Obstructive Pulmonary Disease in Patients With Heart Failure With Preserved Ejection Fraction: Insights From PARAGON‐HF

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2021
Background Little is known about the impact of chronic obstructive pulmonary disease (COPD) in patients with heart failure with preserved ejection fraction (HFpEF).
Leanne Mooney, Nathaniel M Hawkins, P. Jhund, M. Redfield, M. Vaduganathan, A. Desai, Jean L. Rouleau, M. Minamisawa, A. Shah, M. Lefkowitz, M. Zile, D. V. van Veldhuisen, M. Pfeffer, I. Anand, A. Maggioni, M. Senni, B. Claggett, Scott D. Solomon, J. McMurray   +18 more
semanticscholar   +1 more source