Results 101 to 110 of about 16,908,993 (362)
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Doit-on tirer de ce qui précède la conclusion que le couple des frèrespareils et le couple homosexuel sont les seuls viables, à la condition que le premier fonde son existence sur une pratique homosexuelle (« communion séminale » par exemple) ? On pourrait être tenté de répondre par l’affirmative, d’autant que Tournier, dans Le Vent Paraclet (chapitre
openaire +2 more sources
Review of: "Grid-secluded Induction Generator with ANN and Intreval Type-2 Fuzzy based Controller for Wind Power Generation with Smart Load Control" [PDF]
Long Tao
openalex +1 more source
Invasive Weed Optimization Technique-Based ANN to the Prediction of Rock Tensile Strength
In many site investigation phases of civil and mining engineering projects, the tensile strength of the rocks is one of the most significant parameters that must be identified. This parameter can be determined directly through laboratory tests.
Lei Huang +4 more
semanticscholar +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Applying Artificial Neural Networks and Multiple Linear Regression models to estimate Forest density in Marivan forests [PDF]
Studying and modeling quantitative characteristics of forest to develop and direct the ecosystem toward optimal aims and conservative activities is considered as an eminent operation.
sasan vafaei +3 more
doaj

