Results 211 to 220 of about 2,492,284 (306)

Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers

open access: yesAnnals of Neurology, EarlyView.
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang   +45 more
wiley   +1 more source

Hydrogels Under Superchaotropic Control: Polyoxometalate Stabilization and pH‐Responsive Crosslinking in Cellulose Ether Solutions

open access: yesAngewandte Chemie, EarlyView.
Superchaotropic binding of Keggin polyoxometalates (POMs) to non‐ionic biopolymers like cellulose ethers (CEs) stabilizes otherwise hydrolytically unstable POMs in aqueous solution and allows conversion of pH‐nonresponsive polymers into pH‐responsive soft materials. The pH‐driven conversion from plenary to lacunary POMs switches superchaotropic binding
Vighnesh B. Lokare   +3 more
wiley   +2 more sources

A novel phage satellite class induces prophage excision in Mycolicibacterium aichiense. [PDF]

open access: yesVirology
Qian HL   +5 more
europepmc   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source

A Deep‐Red‐Absorbing Osmium(II) Complex as a Photosensitizer for Photodynamic Therapy Inducing Immunogenic Cell Death

open access: yesAngewandte Chemie, EarlyView.
A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang   +12 more
wiley   +2 more sources

Author Correction: Disease exacerbation in human DMD MYOrganoids enables gene therapy evaluation and unveils persistence of fibrotic activity. [PDF]

open access: yesNPJ Regen Med
Palmieri L   +12 more
europepmc   +1 more source

APECx-Anaesthesia, Perfusion and Surgical Practices in Cardiac Surgery: Main Study Protocol of a Modular Multiphase Prospective International Multicentre Observational Study. [PDF]

open access: yesActa Anaesthesiol Scand
Seegers JC   +42 more
europepmc   +1 more source

Time‐Resolved Native Mass Spectrometry Reveals Reversible Light‐Driven Oligomerization of Arabidopsis Cryptochrome 1 and Its Antagonism by BIC1

open access: yesAngewandte Chemie International Edition, EarlyView.
Time‐resolved native mass spectrometry uncovers the blue‐light‐dependent kinetic mechanism of Arabidopsis CRY1 oligomerization, proceeding sequentially from monomers to dimers and tetramers. ATP promotes assembly, whereas BIC1 actively blocks and disassembles tetramers independent of light, providing mechanistic insight into the regulation of ...
Alicia Just   +8 more
wiley   +1 more source

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