Results 171 to 180 of about 119,970 (362)

STAT6 Activation Exacerbates Ferroptosis in Airway Epithelium by Inhibiting PRKN‐Mediated Mitophagy in Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
This study uncovers STAT6‐driven pulmonary fibrosis (PF) via suppression of PRKN‐mediated airway epithelial mitophagy, triggering mitochondrial dysfunction and ferroptosis. Rifabutin is identified as a potent STAT6 inhibitor that effectively reverses fibrotic progression. These findings reveal the STAT6‐PRKN axis as a pathogenic regulator and provide a
Youjing Yang   +7 more
wiley   +1 more source

Harnessing Bifunctional Nitrogen‐Dislocation Interactions for a Record Ultra‐Strong‐and‐Ductile Duplex Titanium Alloy

open access: yesAdvanced Science, EarlyView.
By engineering bifunctional nitrogen‐dislocation interactions, this work constructs a heterogeneous lamellar structure with N‐rich low‐angle boundaries and coherent nanotwinned martensites, enabling ultrahigh yield/tensile strength (1532/1869 MPa) and activating massive dislocations via stress‐driven bow‐out/cross‐slip.
Chongle Zhang   +5 more
wiley   +1 more source

Quantitative Electron Beam‐Single Atom Interactions Enabled by Sub‐20‐pm Precision Targeting

open access: yesAdvanced Science, EarlyView.
Atomic lock‐on (ALO) is a rapid, low‐dose in situ technique in scanning transmission electron microscopy (STEM) that achieves sub‐20 picometer (pm) beam positioning. A sparse annular scan collects positional information while avoiding irradiation of the target site.
Kevin M. Roccapriore   +2 more
wiley   +1 more source

Designing Spin Symmetry for Altermagnetism with Strong Magnetoelectric Coupling

open access: yesAdvanced Science, EarlyView.
Antiferromagnets can be induced into altermagnets by changing the real‐space symmetry, increasing their potential for use in spintronic devices. Here, a novel and general approach is proposed: transforming antiferromagnets into altermagnets by modulating spin‐space symmetry, rather than real‐space symmetry.
Wei Sun   +6 more
wiley   +1 more source

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