Results 151 to 160 of about 1,239 (198)

Cross‐ancestry polygenic risk scores enhance Alzheimer's disease risk prediction in multiethnic cohorts

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Genome‐wide association studies (GWAS) have identified 80+ genetic loci associated with Alzheimer's disease (AD), enabling the development of polygenic risk scores (PRS). However, the predictive accuracy of PRS in diverse populations remains low.
Meri Okorie   +9 more
wiley   +1 more source

Stratification by a polygenic risk score of common variation aids in Alzheimer's disease rare variant discovery

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION We utilized an Alzheimer's disease (AD) polygenic risk score (PRS) to discover associations with novel rare variants (RVs). METHODS PRSs for European ancestry (EA) participants of the Alzheimer's Disease Sequencing Project were calculated using summary statistics from a large genome‐wide association study.
Oluwatosin Olayinka   +13 more
wiley   +1 more source

Frontline Nurse Managers' Views of Person‐Centred Management in a Private Hospital: A Qualitative Study

open access: yesNursing Open, Volume 13, Issue 8, August 2026.
ABSTRACT Aim To explore the perceptions and experiences of frontline nurse managers regarding the person‐centred management approach. Design A qualitative study. Methods The study adopted a qualitative approach to gain an in‐depth understanding of frontline nurse managers' experiences.
Furkan Cihat Arici   +1 more
wiley   +1 more source

After 50 Years of ‘Protocolization’, What Is the Progress Towards Munro's Image of a More Flexible, Innovative and ‘Child‐Centred’ English Child Protection System?

open access: yesChild &Family Social Work, Volume 31, Issue 3, Page 1676-1687, August 2026.
ABSTRACT Fifty years after the formation of England's child protection system, the country continues to reel from new instances of high‐profile child death tragedies where children have been harmed despite practitioners complying with the processes and procedures designed to protect them.
Ciarán Murphy, Michael Murphy
wiley   +1 more source

Managing the Complexity‐Coherence Trade‐Off in Clinical Reasoning: A Two‐Stage Graph Ontology Based on WHO International Classifications

open access: yesJournal of Evaluation in Clinical Practice, Volume 32, Issue 5, August 2026.
ABSTRACT Background Clinical reasoning in contemporary practice often involves ill‐structured, poorly defined problems that span the biopsychosocial domain and require reasoning under high relational complexity. Despite sustained scholarly attention to clinical reasoning, few models are both theoretically grounded and usable for clinicians who face ...
David Kellett
wiley   +1 more source

FREQ‐NESS Reveals Age‐Related Differences in Frequency‐Resolved Brain Networks During Auditory Recognition and Resting State

open access: yesAnnals of the New York Academy of Sciences, Volume 1562, Issue 1, August 2026.
We adapted the FREQ‐NESS pipeline to event‐related MEG data from 140 adults during a melody‐recognition task, revealing an age‐related reorganization of frequency‐specific brain networks. Younger adults showed task‐related reduction in the prominence of alpha networks, whereas older adults maintained prominent slower alpha networks (8.6–10.0 Hz) across
Chiara Malvaso   +8 more
wiley   +1 more source

Development of a Diabetes Rural Stakeholder Research Team and Patient-Centered Research Agenda. [PDF]

open access: yesOTJR (Thorofare N J)
Jewell VD   +10 more
europepmc   +1 more source

Hunting and Hauora: Pig Hunters and Poaka in Aotearoa New Zealand

open access: yesNew Zealand Geographer, Volume 82, Issue 2, August 2026.
ABSTRACT Though invasive, wild pigs (poaka) were fundamental to the survival of both Māori and Pākehā during colonisation, and they remain an essential source of kai (sustenance) today. Utilising a Whanganui case study, 24 participants, semi‐structured interviews, and thematic analysis guided by Kaupapa Māori principles, describe hunters' interests in ...
Claire Kuuii Adeline Dowsett   +2 more
wiley   +1 more source

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