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Three new megastigmanes from the leaves of Annona muricata

Journal of Natural Medicines, 2011
Three new megastigmanes (1-3), named annoionols A and B (1, 2) and annoionoside (3), were isolated from the leaves of Annona muricata L. (Annonaceae) together with 14 known compounds (4-17). Among the known compounds, annoionol C (4) was isolated from a natural source for the first time.
Hideaki Otsuka   +2 more
exaly   +3 more sources

Cytotoxicity and antileishmanial activity of Annona muricata pericarp

Fitoterapia, 2000
Hexane, ethyl acetate and methanol extracts of Annona muricata pericarp were tested in vitro against Leishmania braziliensis and L. panamensis promastigotes, and against cell line U-937. The ethyl acetate extract was more active than the other extracts and even of Glucantime used as reference substance.
M C, Jaramillo   +4 more
openaire   +2 more sources

Murihexol, a linear acetogenin from Annona muricata

Phytochemistry, 1998
Murihexol (1), a novel acetogenin, and three known ones, donhexocin (2), annonacin A and annonacin, have been isolated from the seeds of Annona muricata. Compound 1 is a C(35) acetogenin without any THF rings, with six hydroxyls in the long aliphatic chain.
Jing Guang, Yu   +3 more
openaire   +2 more sources

Annona muricata (soursop).

2021
Abstract A. muricata is a small evergreen tree up to 9 m tall. It is native to tropical America but is widely planted in home gardens in South-East Asia. In Brazil, several small commercial plantations are in operation (about 2000 hectares are planted) with more planned.
Marianne Jennifer Datiles   +1 more
openaire   +1 more source

Antiparasitic Activity ofAnnona muricataandAnnona cherimoliaSeeds

Planta Medica, 1991
Methanolic extracts of Annona muricata and A. cherimolia (Annonaceae) seeds were tested for antiparasitic activity against E. histolytica, N. brasiliensis, M. dessetae and A. salina. The acetogenins isolated from these extracts are found to be responsible for the important activity on infective larvae of Molinema desetae.
C, Bories   +7 more
openaire   +2 more sources

Overcoming multi drug resistance mediated by ABC transporters by a novel acetogenin- annonacin from Annona muricata L.

Journal of Ethnopharmacology, 2023
ETHNOPHARMACOLOGICAL RELEVANCE Multi-Drug Resistance (MDR), mediated by P-glycoprotein (P-gp) is one of the barriers to successful chemotherapy in colon cancer patients. Annona muricata L.
J. Manoharan   +2 more
semanticscholar   +1 more source

Anti‐Phytopathogenic and Phytotoxic Effects of Annona glabra Lin. and Annona muricata Lin. Seed Extracts: In vitro and In vivo Assessment, Bioactive Compound Quantification, and Mechanism Involved

ChemistrySelect
Building upon prior research demonstrating the excellent antifungal and nematicidal efficacy of Annona squamosa Lin. seed extracts, this study extends its scope to investigate similar properties in seed extracts from two other Annonaceae species: Annona ...
Quang-Le Dang   +14 more
semanticscholar   +1 more source

Untargeted metabolomics using UHPLC-Q-Orbitrap HRMS for identifying cytotoxic compounds on MCF-7 breast cancer cells from Annona muricata Linn leaf extracts as potential anticancer agents.

Phytochemical Analysis
INTRODUCTION The leaves of Annona muricata L., known as "soursop" or "sirsak" in Indonesia, are used traditionally for cancer treatment. However, the bioactive components remain largely unidentified.
D. Septaningsih   +4 more
semanticscholar   +1 more source

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