Results 121 to 130 of about 504,433 (243)

Dataset of audiovisual unscripted monologues with speech annotations. [PDF]

Data Brief
Jaeger M, Daeglau M, Grimm G, Bleichner MG.   +3 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

AEGIS: an annotation extraction and genomic integration resource. [PDF]

Bioinformatics
Navarro-Payá D, Santiago A, Velt A, Moretto M, Rustenholz C, Matus JT.   +5 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A Step-by-Step Protocol From METASPACE to Biological Interpretation. [PDF]

J Mass Spectrom
Moreno-Pedraza A, Gorman B, Velickovic M, Bentelspacher M, Barros J, Velickovic D, Anderton CR.   +6 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Full-length transcriptome of Oocystis borgei under stress condition

Frontiers in Genetics, 2023
Chengcheng Deng, Jiajia Ren, Ting Hong, Yang Liu, Feng Li, Yulei Zhang, Changling Li, Zhongdian Dong, Xianghu Huang, Ning Zhang, Ning Zhang   +10 more
doaj   +1 more source

Appendix300: Surgical video and patient metadata of 330 laparoscopic appendectomy cases from five institutions. [PDF]

Sci Data
Kolbinger FR, Kirchner M, Pfeiffer K, Bodenstedt S, Jenke AC, Barthel J, Carstens M, Dehlke K, Dietz S, Emmanouilidis S, Fitze G, Freitag M, Holderried F, Jacobi T, Kanjo W, Leitermann L, Mees ST, Pistorius S, Prudlo C, Seiberth A, Schultz J, Thiel K, Ziehn D, Speidel S, Weitz J, Kather JN, Distler M, Saldanha OL.   +27 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Integrating Functional Consequence Annotation With PAH Allelic Phenotype Values Refines Prediction of Tetrahydrobiopterin Responsiveness. [PDF]

J Inherit Metab Dis
Himmelreich N, Blau N.
europepmc   +1 more source