Results 251 to 260 of about 747,925 (322)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

CellPredX, a computational framework for cross-data type, cross-sample, and cross-protocol cell type annotation through domain adaptation and deep metric learning. [PDF]

PLoS Comput Biol
Liu Y, Xia Y, Yan H, Shen LC, Zhu Y, Qiang JP, Wei G.   +6 more
europepmc   +1 more source

Annotations to 3D Models for Collaborative Design Review

, 2004
Hiroshi Masuda, Yasuhiro Yoshioka, Akio Wada, Hiroyuki Yamato   +3 more
openalex   +2 more sources

Annote bene [PDF]

Nature Genetics, 1999
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A supervised Bayesian method for time (re)annotation of transcriptomics data. [PDF]

NAR Genom Bioinform
Nushi E, Douillard FP, Selby K, Blount BA, Pennington OJ, Minton NP, Lindström M, Honkela A.   +7 more
europepmc   +1 more source

A study on annotations of 『HyubjooMyunghyunShibChoSi(夾注名賢十抄詩)』 - focused on Shilla(新羅) poems

, 2012
EujJeong Kim
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Ensembl’s regulatory annotation for human, mouse, livestock, and aquaculture species

Ilsley GR, Lins PRB, Merino GA, Urbina-Gómez D, Harrison PW.   +4 more
europepmc   +1 more source

SMART v10: three decades of the protein domain annotation resource. [PDF]

Nucleic Acids Res
Letunic I, Bork P.
europepmc   +1 more source