Results 281 to 290 of about 1,137,186 (320)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Analytical Validation of an Annotation Tool for WGS-Based Pharmacogenomics: Preparing for Clinical Implementation in Pediatric Oncology. [PDF]

open access: yesClin Transl Sci
Diekstra MHM   +9 more
europepmc   +1 more source

Assessing Impact of Data Quality in Early Post-Operative Glioblastoma Segmentation. [PDF]

open access: yesJ Imaging
Helland RH   +5 more
europepmc   +1 more source

Validation of conformal prediction in cervical atypia classification. [PDF]

open access: yesSci Rep
Hagos MT   +8 more
europepmc   +1 more source

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