Results 71 to 80 of about 1,035,013 (320)
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Genome-Wide SNP Discovery in Indigenous Cattle Breeds of South Africa
Single nucleotide polymorphism arrays have created new possibilities for performing genome-wide studies to detect genomic regions harboring sequence variants that affect complex traits. However, the majority of validated SNPs for which allele frequencies
Avhashoni A. Zwane+11 more
doaj +1 more source
To explore the characteristics of the mitogenome of Melyridae and reveal phylogenetic relationships, the mitogenome of Cordylepherus sp. was sequenced and annotated. This is the first time a complete mitochondrial genome has been generated in this family.
Lilan Yuan+4 more
doaj +1 more source
Annotation Tools in Gastrointestinal Polyp Annotation
Capsule endoscopy (CE) is a valid alternative to conventional gastrointestinal (GI) endoscopy tools. In CE, annotation tools are crucial in developing large and annotated medical image databases for training deep neural networks (DNN). We provide an overview of the described and in-use various annotation systems available, focusing on the annotation of
Ola Selnes+4 more
openaire +4 more sources
A text-based approach to the ImageCLEF 2010 photo annotation task [PDF]
The challenges of searching the increasingly large collections of digital images which are appearing in many places mean that automated annotation of images is becoming an important task. We describe our participation in the ImageCLEF 2010 Visual Concept
Jones, Gareth J.F.+2 more
core +2 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
In this article, we assess the interest of the recently introduced multiscale scattering transform for texture classification applied for the first time in plant science.
Pejman Rasti+4 more
doaj +1 more source
Interdyscyplinarne perspektywy rozwoju, integracji i zastosowań ontologii poznawczych [PDF]
We discuss recent progress in the development of cognitive ontologies and summarize three challenges in the coordinated development and application of these resources. Challenge 1 is to adopt a standardized definition for cognitive processes. We describe
Joanna Hastings+9 more
doaj +1 more source
GNPAnnot community annotation system applied to sugarcane bac clone sequences (W572) [PDF]
A large amount of data is being produced by current genome sequencing projects. Sequence annotations and analyses need to be organized into databases and widely accessible.
Bocs, Stéphanie+5 more
core