Results 71 to 80 of about 503,379 (243)

Writing Names in Music Books. Case Studies from the Viadrina Collection Held in the Music Department at University of Warsaw Library

open access: yesMuzyka
The Music Department at University of Warsaw Library houses a corpus of musical sources originating from the library of Viadrina University in Frankfurt an der Oder, predominantly comprising musical prints from the late sixteenth to early seventeenth ...
Antonio Chemotti
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Ranking Biomedical Annotations with Annotator’s Semantic Relevancy [PDF]

open access: yesComputational and Mathematical Methods in Medicine, 2014
Biomedical annotation is a common and affective artifact for researchers to discuss, show opinion, and share discoveries. It becomes increasing popular in many online research communities, and implies much useful information. Ranking biomedical annotations is a critical problem for data user to efficiently get information.
openaire   +3 more sources

Discovering Object Stories: Linking Unstructured Museum Data Through Semantic Annotation

open access: yesJournal of Open Humanities Data
This paper explores the application of Recogito Studio for annotating unstructured museum data to create semantic links and visualisations. The study focuses on a sample dataset from National Museums Scotland, which includes metadata about navigational ...
Sarah Middle   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Complete mitochondrial genome of Stichaeus nozawae Jordan & Snyder 1902 (Zoarcales: Stichaeidae)

open access: yesMitochondrial DNA. Part B. Resources, 2019
We report on the structure and composition of the first complete mitochondrial genome of Stichaeus nozawae (typical prickleback fish (Zoarcales, Stichaeidae)), obtained by dideoxy (Sanger) sequencing technique.
Sergei V. Turanov   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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