Results 101 to 110 of about 479,142 (270)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda +15 more
wiley +1 more source
NoGOA: predicting noisy GO annotations using evidences and sparse representation
BMC Bioinformatics, 2017 Background Gene Ontology (GO) is a community effort to represent functional features of gene products. GO annotations (GOA) provide functional associations between GO terms and gene products.
Guoxian Yu, Chang Lu, Jun Wang
doaj +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
IEEE AccessIn this work, we investigate the connection between browsing behavior and task quality of crowdsourcing workers performing annotation tasks that require information judgements. Such information judgements are often required to derive ground truth answers
Pei-Chi Lo, Ee-Peng Lim
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Estimating the annotation error rate of curated GO database sequence annotations
BMC Bioinformatics, 2007 Background Annotations that describe the function of sequences are enormously important to researchers during laboratory investigations and when making computational inferences.
Brown Alfred L +2 more
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Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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قيود العالم الموسوعي إبراهيم الحلبي المداري : تحليل وتقييم
Yakın Doğu Üniversitesi İslam Tetkikleri Merkezi Dergisiيُعتبر إبراهيم الحلبي المداري (1190هـ/1776م) أحد العلماء الموسوعيين في القرن الثاني عشر الهجري/الثامن عشر الميلادي؛ حيث برعَ في علم الكلام والفقه والتصوف والمنطق وعلوم اللغة والفلك والرياضيات وغيرها، وتركَ في كُلِّ فنٍّ كتابًا على الأقل.
Münzir Şeyhhasan
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source