Results 181 to 190 of about 14,630 (260)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Robot-Assisted Distal Pancreatectomy for Pancreatic Cancer with Type IIIa Portal Annular Pancreas Using a Novel Strategy of Ventral Pancreas Preservation: A Case Report. [PDF]

Surg Case Rep
Noso T, Hioki M, Doi R, Hara K, Shimomi R, Nishimura S, Mishima K, Miura N, Kagawa T, Ishikawa W, Kurose Y, Nobuoka D, Asami S, Sadamori H, Takakura N.   +14 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Doming Volume in Mitral Valve Prolapse: Pathophysiology, Imaging Implications and Clinical Relevance. [PDF]

J Cardiovasc Dev Dis
Mangini F, Dentamaro I, Grimaldi M, Guglielmo M, Guaricci AI, Spinelli F, Musella F, Iliceto S, Di Monaco A, Dellegrottaglie S, Quarta S, Sgarra L, Novielli G, Biederman RWW, Suma S, Marazia S, Citarelli G, Calbi R.   +17 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Transforaminal intradiscal steroid injection versus transforaminal epidural steroid injection for chronic discogenic low back pain with active discopathy: a randomized controlled trial protocol. [PDF]

Front Med (Lausanne)
Song J, Liu S, Lin W, Yao S, Zhang Y, Yi M, Luo Z, Ding L.   +7 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Leaflet Lengths and Commissural Dimensions as the Primary Determinants of Orifice Area in Mitral Regurgitation: A Sobol Sensitivity Analysis. [PDF]

Bioengineering (Basel)
Bagherzadeh A, Keshavarzzadeh V, Hoang P, Kreuzer S, Yao J, Lee LC, Kassab GS, Guccione J.   +7 more
europepmc   +1 more source

Design and Characterization of a Novel Continuous Annular Gap Crystallizer

Organic Process Research & Development
Nico Nys, Lorenz Buchgraber, Peter Neugebauer, Matthew J. Jones, Heidrun Gruber-Woelfler   +4 more
openaire   +1 more source