Results 31 to 40 of about 15,838 (216)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Effects of Electrical Boundary Configurations on Magnetohydrodynamic Flow and Heat Transfer in a Liquid Metal-filled Annulus [PDF]

Journal of Applied Fluid Mechanics
This numerical study investigates magnetohydrodynamic (MHD) flow and heat transfer for liquid metals within a cylindrical annulus subjected to a radial magnetic field.
B. Mahfoud, L. Bouragbi, H. E. Mahfoud
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

PRESSURE AND VELOCITY AMPLITUDES OF THE INCOMPRESSIBLE FLUID IN CONCENTRIC ANNULAR PASSAGE WITH OSCILLATORY BOUNDARY: TURBULENT FLOW [PDF]

Journal of Engineering Science and Technology, 2014
An unsteady program based on a turbulence model called Baseline (BSL) komega model was conducted to simulate three turbulent flows with Re numbers of 4×103, 8×103 and 1×104, between two initially concentric cylinders.
ABOLGHASEM MEKANIK, MOHAMAD ALI YAVARI
doaj  

Annular Air Gap Area Impact on Flame Regime Transition and Combustion in Low-chamber-pressure Air Heater [PDF]

Journal of Applied Fluid Mechanics
This study combines high-speed shadowgraph imaging with numerical simulations to systematically examine the effect of the annular air gap area on the spray combustion characteristics of an alcohol-liquid-oxygen-air tripropellant coaxial direct-flow ...
K. Wang, C. B. Shen, B Fan
doaj   +1 more source

Multi-objective optimization of heating system for rapid thermal cycling molding mold with internal induction heating

SN Applied Sciences, 2021
A rapid thermal cycling molding (RTCM) with novel internal induction heating mode is proposed in this work. The induction coils are directly inserted in the corresponding mounting holes of mold with an annular gap in between.
Cheng-Long Xiao, Cemi Kahve, Chun-Ming Fu   +2 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Effect of central hole on fuel temperature distribution

Nuclear Engineering and Technology, 2017
Reliable prediction of nuclear fuel rod behavior of nuclear power reactors constitutes a basic demand for steady-state calculations, design purposes, and fuel performance assessment.
Mehdi Yarmohammadi, Mohammad Rahgoshay, Amir Saied Shirani   +2 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source