Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs
Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri +10 more
wiley +1 more source
Routine Echocardiographic Assessment in LVAD Patients-A Structured Approach to Acquisition and Interpretation. [PDF]
Merke N +3 more
europepmc +1 more source
Plasmakristall‐4 Experiment: 10 Years of Operation in Orbit
ABSTRACT Plasmakristall‐4 (PK‐4) is a microgravity complex plasma laboratory operated for 10 years on board the International Space Station. Its main purpose is the particle‐resolved investigation of generic condensed matter phenomena using strongly coupled suspensions of microparticles immersed in low‐pressure gas‐discharge plasmas.
M. Pustylnik +3 more
wiley +1 more source
Ostial Left Main Obstruction From Pannus Formation in Severely Stenosed Bioprosthetic Aortic Valve. [PDF]
Shah SD +6 more
europepmc +1 more source
Resonance‐induced restoration of rock permeability degraded by heavy components of crude oil
Resonance‐induced changes occur in filtration properties of sedimentary rocks in crude paraffin oil flow under acoustic vibrations. Experimental data on (a) pressure drop; (b) permeability; (c) pressure at the rock inlet; and (d) pressure at the rock outlet are presented.
Evgenii Riabokon +6 more
wiley +1 more source
Transcatheter aortic valve replacement via femoral artery for aortic regurgitation post-LVAD: a case report. [PDF]
Cheng S +5 more
europepmc +1 more source
Aiming at the scientific frontiers of in situ fluidized mining of deep resources, a deep coal fluidized pipeline lifting system based on hydraulic conveying has been proposed. To solve the issue of particle sedimentation of large particles in horizontal connection sections, a solution involving the installation of guide vane‐type swirlers in the ...
Jiusheng Bao +5 more
wiley +1 more source
Beating-Heart Pulmonary Valve Replacement for Isolated Monocuspid Valve. [PDF]
Abbasi M, Alizada AR, Fallahi NA.
europepmc +1 more source
Warming summers limit reindeer grazing, weakening herbivory pressure in the mountain tundra
Climate change is predicted to alter species interactions by exposing ecosystems to increasingly frequent and intense warm spells. In the mountain tundra, grazing by large herbivores, particularly reindeer, can limit shrub expansion and preserve Arctic plant diversity.
Marianne Stoessel +2 more
wiley +1 more source
Numerical simulation on the pressure distribution of hydraulic jet perforation tunnel in natural gas hydrate reservoirs. [PDF]
Zhou J +7 more
europepmc +1 more source

