Results 41 to 50 of about 3,932,847 (285)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Droplets Transmission Mechanism in a Commercial Wide-Body Aircraft Cabin

open access: yesApplied Sciences, 2022
COVID-19 is a respiratory infectious disease that spreads readily between people, and an urgent issue of passengers’ exposure risk assessment in commercial aircraft has been raised because an aircraft cabin as a confined space may carry and transmit the ...
Benben Kong   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Modeling Mist to Annular Flow Development in the Discharge of a Compressor [PDF]

open access: yes, 2012
A model has been created to describe the development of flow leaving a compressor as it transitions from mist to annular flow. Flow parameters such as the drop size, drop speed, drop concentration, film thickness, and film velocity change as a function ...
Wujek, Scott S., Hrnjak, Predrag S.
core   +1 more source

Influence of annular ratio on coal particles transport during boreholes repair by self-propelled water jet drill bits

open access: yesMeitan kexue jishu
Repairing borehole by self-propelled water jet drill bits is an efficient repair technique for downhole failed boreholes, and improving the borehole repair efficiency of self-propelled drill bits is crucial for enhancing the efficiency of coal mine ...
Jianping WEI   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Usage of extruded diamond multi-injectors for improvement of fuel mixing inside the supersonic combustion chamber

open access: yesScientific Reports, 2023
The main attention of this work is to investigate the usage of diamond multi extruded injectors on the fuel distribution in combustor of scramjet. This study applied the computational technique to simulate the transverse fuel jets released from extruded ...
Hossein Seraj   +3 more
doaj   +1 more source

Numerical Simulation of Effective Hole Cleaning by Using an Innovative Elliptical Drillpipe in Horizontal Wellbore

open access: yesEnergies, 2022
In the drilling of horizontal wells, the drill cuttings tend to settle down on the low side of the annulus due to gravity and form a stationary bed, which results in hole cleaning problems.
Guoshuai Ju, Tie Yan, Xiaofeng Sun
doaj   +1 more source

Uniform metric spaces, annular quasiconvexity and pointed tangent spaces

open access: yesMATHEMATICA SCANDINAVICA, 2011
We establish Väisälä's tangent space characterization for uniformity in the doubling metric space setting. We present similar results for other geometric properties.
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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