Results 111 to 120 of about 42,057 (291)

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra   +4 more
wiley   +1 more source

Sudan at War With Itself: Civilian Devastation in the Civil War

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT A civil war is raging in Sudan between the Sudan Armed Forces (SAF) and the Rapid Support Forces (RSF) along with militia groups. Beginning on April 15, 2023, and continuing at least to this writing (October 15, 2025), civilian noncombatants have been subjected to bombings, beatings, torture, shootings, rape, and murder on a large scale. Since
Daniel Rothbart   +3 more
wiley   +1 more source

Annulations...

open access: yesAutour de la seconde guerre mondiale, 2020
openaire   +2 more sources

Breadth at the Helm: Generalist CEOs and Corporate ESG Performance‐Evidence From China

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Drawing on the Upper Echelons Theory and the Imprinting Theory, this study conjectures that generalist CEOs may have a stronger tendency to pursue environmental, social and governance (ESG) goals. We perform multiple regression analyses with observations of Shanghai and Shenzhen A‐share listed companies from 2010 to 2023 in order to explore ...
Shanmei Luo   +4 more
wiley   +1 more source

Mosaic activation of the zebrafish hsp70l heat shock promoter: Implications for interpreting transgenes

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley   +1 more source

ANNULMENT OF A TRADEMARK FOR BAD FAITH [PDF]

open access: yesChallenges of the Knowledge Society
When entering any new potential market or trying to establish a name for oneself on a designated market, one of the first steps taken by any economic operator, apart from actually rendering the service or conceiving the product which is envisaged to be
Roxana CATEA
doaj  

A Commentary on “Comparing Operationalizations of Eating Disorder Recovery Using a Comprehensive Lens: Physical, Behavioral, and Cognitive Domains” by Bardone‐Cone et al.

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Defining recovery in eating disorders remains a major challenge due to the absence of standardized, empirically validated criteria. Bardone‐Cone et al. (2025) address this gap by testing multidimensional, transdiagnostic recovery criteria spanning physical, behavioral, and cognitive domains.
Charlotte Bovenberg   +3 more
wiley   +1 more source

Safeguarding Online Research in Eating Disorders Against Fraud: Increasing Risks and Practical Recommendations

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Recent growth of online research has been accompanied by an increase in reports of fraudulent participants, which can significantly comprise research validity. Drawing from our experience using Qualtrics with open recruitment, existing literature, and emerging studies in eating disorders (ED), we outline the risk and provide simple ...
Jamie‐Lee Pennesi   +2 more
wiley   +1 more source

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