Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Annulus fracture underlies radiation-induced sperm dysfunction revealed by multimodal nano-imaging. [PDF]
Chen N +7 more
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Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Integrative Taxonomy of <i>Agaricus</i> subgen. <i>Pseudochitonia</i> in Arid Northwestern China: Species Diversity and Habitat-Associated Morphological Differentiation. [PDF]
Qi Z +8 more
europepmc +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Balloon Sizing-Guided Valve Selection for Transcatheter Aortic Valve Replacement in Bicuspid Aortic Valve. [PDF]
Satomi N +9 more
europepmc +1 more source
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Reconstruction of the Aorto-Mitral Curtain in Complex Infective Endocarditis: A Contemporary Narrative Review of the Commando Procedure. [PDF]
Lai Y +5 more
europepmc +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
A case report: Transcatheter aortic valve replacement via femoral artery for aortic regurgitation post-CARVAR. [PDF]
Li L, Zhou Z, Wang X, Yin L, Zhang S.
europepmc +1 more source

