Results 41 to 50 of about 2,252,762 (303)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

THE MYSTICAL STANCE: THE EXPERIENCE OF SELF‐LOSS AND DANIEL DENNETT'S “CENTER OF NARRATIVE GRAVITY”

open access: yesZygon, 2014
For centuries, mystically inclined practitioners from various religious traditions have articulated anomalous and mystical experiences. One common aspect of these experiences is the feeling of the loss of the sense of self, referred to as “self‐loss ...
doaj   +2 more sources

An evolutionary approach to anomalous intuition [PDF]

open access: yes, 2011
Intuition has always been associated with a hint of the anomalous, with credible examples of intuitive knowledge that appear to arise from the future or from distant locations without sensory mediation.
Broughton, Richard S
core  

Benefattori dall’aldilà: i lasciti per i lavori edilizi di pubblica utilità a Bologna (secoli XIII e XIV)

open access: yes, 2021
La trattazione riguarda i benefattori, i donatori che hanno deciso a Bologna di contribuire al bene comune non tramite le tradizionali istituzioni caritatevoli, quali ospedali, conventi e monasteri, ma anche attraverso l’investimento dei loro beni nel ...
Edward Loss
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Ontology-driven hypothesis generation to explain anomalous patient responses to treatment [PDF]

open access: yes, 2009
Within the medical domain there are clear expectations as to how a patient should respond to treatments administered. When these responses are not observed it can be challenging for clinicians to understand the anomalous responses. The work reported here
Hughes, Martin   +26 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Clinical Significance of Venous Anomalies in Syndromic Craniosynostosis

open access: yesPlastic and Reconstructive Surgery, Global Open, 2018
Background:. The pattern of cranial venous drainage in syndromic craniosynostosis is unpredictable and not adequately understood. Collateral channels substitute for stenotic venous sinuses and pose potential risk for surgical intervention. The purpose of
Andrea E. Copeland, BSc   +6 more
doaj   +1 more source

Summer Cyclones and Their Association With Short-Term Sea Ice Variability in the Pacific Sector of the Arctic

open access: yesFrontiers in Earth Science, 2021
We investigate the effects of summer cyclones on sea ice within the Pacific sector of the Arctic by analyzing the surface energy flux and wind forcing from a large sample of cyclones.
Peter M. Finocchio, James D. Doyle
doaj   +1 more source

Anomalous energy losses in fractal medium

open access: yes, 2010
We derive equation describing distribution of energy losses of the particle propagating in fractal medium with quenched and dynamic heterogeneities.
Panyukov, Sergey, Leonidov, Andrei
openaire   +2 more sources

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