Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu +14 more
wiley +1 more source
Anomaly detection in urban lighting systems using autoencoder and transformer algorithms. [PDF]
Śmiałkowski T, Czyżewski A.
europepmc +1 more source
Strong Proton‐Phonon Coupling Drives Fast Ion Transport in Perovskites
Experimental and computational phonon analysis of ABO3‐type proton conductor BaSnO3 shows that substitution on the B‐site with yttrium forms an imaginary phonon mode which is instrumental for the function as proton conductor. This overcompensates the adverse proton trapping effect of the yttrium.
Alexey Rulev +8 more
wiley +1 more source
Development of Teleoperated Robotic System for Remote Intraocular Microsurgery
A teleoperated robotic system, characterized by micrometer‐scale precision and a remote center of motion design, is developed and validated to ensure the safety and flexibility of remote intraocular surgery. This system exhibits superior performance in experimental evaluations and holds significant potential for advancing remote microsurgery ...
Andi Xu +30 more
wiley +1 more source
Semantic-aware reinforcement and ensemble learning for signal management and anomaly detection in IoT systems. [PDF]
Wali S, Khan MI, Imran M.
europepmc +1 more source
Magnetic Anisotropy Modulation via van der Waals Gap Engineering in 2D Ferromagnet Fe4GeTe2
This study demonstrates a new route to control magnetic anisotropy in 2D ferromagnets via van der Waals gap engineering. In Fe4GeTe2, an interface‐induced vdW gap expansion is found to anomalously enhance in‐plane magnetic anisotropy while suppressing the spin reorientation transition.
Weiran Xie +13 more
wiley +1 more source
Autonomous cyber-physical security middleware for IoT: anomaly detection and adaptive response in hybrid environments. [PDF]
Ortiz-Garcés I +2 more
europepmc +1 more source
From anomaly detection to rumour detection using data streams of social platforms
Thành Tâm Nguyên +5 more
openalex +2 more sources
Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen +14 more
wiley +1 more source

