Results 91 to 100 of about 218,065 (346)

Cyclic nucleotide signalling in malaria parasites [PDF]

Open Biology, 2017
The cyclic nucleotides 3′, 5′-cyclic adenosine monophosphate (cAMP) and 3′, 5′-cyclic guanosine monophosphate (cGMP) are intracellular messengers found in most animal cell types.
David A. Baker, Laura G. Drought, Christian Flueck, Stephanie D. Nofal, Avnish Patel, Maria Penzo, Eloise M. Walker   +6 more
doaj   +1 more source

Batch Synthesis of Primaquine Diphosphate Anti‐Malarial Drug

Chemistry – A European Journal, EarlyView.
According to the WHO, a child under the age of five dies every 2 minutes from malaria in Africa. It is therefore paramount that access and availability of anti‐malarial drugs must be improved. We report a process for the synthesis of Primaquine Diphosphate, where key intermediates were obtained in a much shorter reaction time compared to processes ...
Faith M. Akwi, Simthandile Swartbooi, Paul Watts   +2 more
wiley   +1 more source

Risk factors for house-entry by malaria vectors in a rural town and satellite villages in The Gambia. [PDF]

, 2008
Background: In the pre-intervention year of a randomized controlled trial investigating the protective effects of house screening against malaria-transmitting vectors, a multi-factorial risk factor analysis study was used to identify factors that ...
Conway, D., Green, C., Jasseh, M., Kirby, M. J., Lindsay, S.W., Milligan, P.M., Sismanidis, C.   +6 more
core   +4 more sources

Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission

Nature, 2019
Bites of Anopheles mosquitoes transmit Plasmodium falciparum parasites that cause malaria, which kills hundreds of thousands of people every year.
D. Paton, L. Childs, Maurice A Itoe, Inga E. Holmdahl, C. Buckee, F. Catteruccia   +5 more
semanticscholar   +1 more source

Updated list of Anopheles species (Diptera: Culicidae) by country in the Afrotropical Region and associated islands

Zootaxa, 2020
The distributions of the Afrotropical Anopheles mosquitoes were first summarized in 1938. In 2017, an extensive geocoded inventory was published for 48 sub-Saharan African countries, including information such as sampling methods, collection dates ...
S. Irish, D. Kyalo, R. Snow, M. Coetzee
semanticscholar   +1 more source

AgamOBP1‐Directed Discovery of Repellents to Control the Spread of Mosquito‐Borne Diseases

ChemMedChem, EarlyView.
Toward the discovery of novel mosquito repellents, a library of potential binders of AgamOBP1 (secondary amines) generated from two amines and seven aldehydes was designed aiming to enable interactions with critical amino acids at the DEET‐site and to bridge the DEET‐ and Icaridin sIC‐binding pockets. 1H STD NMR spectroscopy in the presence of AgamOBP1
Evanthia Chazapi, Eftichia Kritsi, Constantinos Potamitis, Panagiota G. V. Liggri, Katerina E. Tsitsanou, Christina E. Drakou, Antonios Michaelakis, Dimitrios P. Papachristos, Spyros E. Zographos, Maria Zervou, Theodora Calogeropoulou   +10 more
wiley   +1 more source

Comparative Field Evaluation of Combinations of Long-Lasting Insecticide Treated Nets and Indoor Residual Spraying, Relative to Either Method Alone, for Malaria Prevention in an Area where the main Vector is Anopheles Arabiensis. [PDF]

, 2013
Long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are commonly used together in the same households to improve malaria control despite inconsistent evidence on whether such combinations actually offer better protection than nets ...
A Bhattarai, A Cohuet, A Ogbonna, A Smith, Alex J Ntamatungiro, AM Eijk, AM Noor, AN Clements, C Drakeley, C Ngufor, CF Curtis, D Chandramohan, Deo R Kavishe, Edgar Mbeyela, Elizabeth Turner, FO Okumu, FO Okumu, FO Okumu, FO Okumu, FO Okumu, FO Okumu, Fredros O Okumu, G Fegan, G MacDonald, GF Killeen, Godfrey Lingamba, H Ranson, H Reyburn, HM Ferguson, I Kleinschmidt, J Beier, J Beier, J Kitau, JA Scott, Jason Moore, JM Mwangangi, JP Grieco, JT Griffin, KI Barnes, KI Barnes, L Yakob, Lena M Lorenz, LF Tseng, LL Koekemoer, M Akogbeto, M Over, MI Msellem, Michael G Kenward, MJ Hamel, ML Mabaso, MN Bayoh, MOH-Zambia, N Chitnis, NJ Govella, PM Nyarango, R Carter, R Development Core Team, RA Khatib, RJ Kent, RL Kouznetsov, S Abdulla, Sarah J Moore, SB Ogoma, SE Clarke, The malERA Consultative Group on Vector Control, TL Russell, TL Russell, V Corbel, W Takken, WA Hawley, WA Hawley, WHO, WHO, WHO, WHO, WHO, WHO, YA Derua   +77 more
core   +3 more sources

Geographical distribution of Anopheles stephensi in eastern Ethiopia

Parasites & Vectors, 2019
The recent detection of the South Asian malaria vector Anopheles stephensi in Ethiopia and other regions in the Horn of Africa has raised concerns about its potential impact on malaria transmission.
M. Balkew, P. Mumba, Dereje Dengela, Gedeon Yohannes, Dejene Getachew, Solomon Yared, Sheleme Chibsa, M. Murphy, Kristen George, K. Lopez, D. Janies, Sae Hee Choi, Joseph D. Spear, S. Irish, Tamar E. Carter   +14 more
semanticscholar   +1 more source

Anopheles mosquitoes reveal new principles of 3D genome organization in insects

Nature Communications, 2020
Chromosomes are hierarchically folded within cell nuclei into territories, domains and subdomains, but the functional importance and evolutionary dynamics of these hierarchies are poorly defined.
V. Lukyanchikova, Miroslav Nuriddinov, P. Belokopytova, A. Taskina, Jiangtao Liang, M. Reijnders, Livio Ruzzante, Romain Feron, Robert M. Waterhouse, Yang Wu, Chunhong Mao, Z. Tu, I. Sharakhov, V. Fishman   +13 more
semanticscholar   +1 more source

A Possible Case of β‐Thalassemia From the Cemetery of Santa Maria Maggiore in Vercelli (Piedmont, Northern Italy,18th Century)

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT In Italy's Piedmont region, the city of Vercelli has a history of malaria transmission due to favorable conditions for Anopheles mosquitoes, which may have influenced the genetic prevalence of thalassemia. This study investigates the skeletal remains of a nonadult individual from the Church of Santa Maria Maggiore in Vercelli, dating to the ...
R. Fusco, C. Tesi, A. Mazzucchi, A. Vanni, M. Licata   +4 more
wiley   +1 more source