Results 81 to 90 of about 47,434 (237)
Recent advances in understanding and managing chronic constipation [version 1; referees: 2 approved]
F1000Research, 2018 Constipation, a condition characterized by heterogeneous symptoms, is common in Western society. It is associated with reduced physical health, mental health, and social functioning.
David O. Prichard, Adil E. Bharucha
doaj +1 more source
Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a. [PDF]
, 2016 A comprehensive genomic and proteomic, computational, and physiological approach was employed to examine the (previously unexplored) role of microRNAs (miRNAs) as regulators of internal anal sphincter (IAS) smooth muscle contractile phenotype and basal ...
Addya, Sankar +6 more
core +3 more sources
JPGN Reports, Volume 7, Issue 1, Page 55-58, February 2026.ABSTRACT Severe refractory constipation can lead to fecal retention requiring hospitalization, nasogastric cleanout, or manual disimpaction, and in some cases, surgery. Neostigmine, a reversible acetylcholinesterase inhibitor, is commonly used for pseudo‐obstruction but rarely for refractory constipation. Here, we report a 21‐year‐old male with chronic
Mojdeh Mostafavi +2 more
wiley +1 more source
Image of the Month: Decision-Making in Surgery for Late Onset Hirschsprung Disease
European Journal of Pediatric Surgery Reports, 2020 We present a case of a 14-year-old boy with chronic distension, poor growth, and chronic constipation. He undergoes anorectal manometry and rectal biopsy, confirming the diagnosis of Hirschsprung disease (HD).
Anisha Apte +2 more
doaj +1 more source
United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.ABSTRACT Background Bowel urgency (BU) is reported by over 80% of patients with ulcerative colitis (UC) and 60% of those with Crohn's disease (CD). However, the impact of advanced therapies on BU has not been consistently evaluated. Objectives To assess the effect of advanced therapies on BU improvement in patients with UC and CD.
Ferdinando D'Amico +17 more
wiley +1 more source
Clinical value of motor function of digestive system investigation: past, present and future
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2013 The aim of review. To demonstrate modern methods of investigation of motor function of the esophagus, stomach, small and large intestine, anorectal area and their clinical value.Key points.
A. S. Trukhmanov +2 more
doaj
Research progress on the etiology and treatment of functional anorectal pain
结直肠肛门外科Functional anorectal pain (FAP) is a functional gastrointestinal disorder characterized by chronic or recurrent pain in the anorectal region. Clinical diagnosis relies on multimodal evaluation, including medical history, physical examination, anorectal ...
Bai Xinxin +3 more
doaj +1 more source
Heliyon, 2018 The aim of this study is to evaluate if a gel of bacterial cellulose gel can revert the loss of anal resting pressure after anorectum sphincter injury in rat model, elected as a model to simulate fecal incontinence.
Aline Ribeiro Teixeira Cavalcante +7 more
doaj +1 more source
Effect of Octreotide on the Colonic Motility in Pediatric Patients with Chronic Recalcitrant Constipation [PDF]
, 2015 Objective: The aim of the present study was to study the effect of octreotide on colonic motility in pediatric patients with recalcitrant chronic constipation/encopresis and other suspected colonic motility disorders. Methods: This was a nonrandomized,
Croffie, Joseph +4 more
core +2 more sources
Colorectal Disease, Volume 28, Issue 2, February 2026.Abstract Background Anorectal incontinence is a major health issue due to its economic burden and impact on quality of life. Its true prevalence remains under‐estimated and a matter of debate. Our aim was to evaluate the prevalence of anal incontinence among the collaborators of a tertiary hospital.
Alexandre Balaphas +8 more
wiley +1 more source