Results 31 to 40 of about 157,317 (312)

Early-onset anorexia nervosa: a scoping review and management guidelines

Journal of Eating Disorders
Background Anorexia nervosa (AN) is a serious multifactorial eating disorder characterized by insufficient nutritional intake to maintain a minimum normal weight for one's age and height, a fear of gaining weight and a distorted body image.
Anaël Ayrolles, Julia Clarke, Nathalie Godart, Céline André-Carletti, Clémentine Barbe, Anne Bargiacchi, Corinne Blanchet, Florence Bergametti, Valérie Bertrand, Emmanuelle Caldagues, Marylene Caquard, Danielle Castellotti, Richard Delorme, Laurence Dreno, Dominique Feneon Landou, Priscille Gerardin, Selim Guessoum, Ludovic Gicquel, Juliane Léger, Stéphanie Legras, Lucile Noel, Anne Fjellestad-Paulsen, Hélène Poncet-Kalifa, Flora Bat-Pitault, Coline Stordeur   +24 more
doaj   +1 more source

Chronic stress and adipose tissue in the anorexic state: endocrine and epigenetic mechanisms

Adipocyte, 2020
Although adipose tissue metabolism in obesity has been widely studied, there is limited research on the anorexic state, where the endocrine system is disrupted by reduced adipose tissue mass and there are depot-specific changes in adipocyte type and ...
Yang Xiao, Dongmin Liu, Mark A. Cline, Elizabeth R. Gilbert   +3 more
doaj   +1 more source

Diagnostic reasoning in rehabilitation nutrition: Position paper by the Japanese Association of Rehabilitation Nutrition (secondary publication)

Journal of General and Family Medicine, 2022
Diagnostic reasoning is the thought process used to arrive at a diagnosis based on symptoms, examination findings, and laboratory values. Diagnosis is categorized as nonanalytic reasoning (intuition) and analytic reasoning (analysis).
Hidetaka Wakabayashi, Keisuke Maeda, Ryo Momosaki, Yoji Kokura, Yoshihiro Yoshimura, Dai Fujiwara, Shintaro Kosaka, Norio Suzuki   +7 more
doaj   +1 more source

Multimodal Imaging Reveals Cerebral Microcirculation Dynamics and Mechanisms in Mouse Central Nervous System After Intranasal Infection With Recombinant Pseudorabies Virus

Advanced Science, EarlyView.
Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling, Chongxin Wu, Mengxuan Gui, Kaiyun Chen, Yanbo Yang, Jiwei Xing, Fengxian Du, Wei Liao, Luyao Yang, Zhaokui Jin, Ningshao Xia, Guosong Wang, Yixin Chen, Qingliang Zhao   +13 more
wiley   +1 more source

Substance P and Glucagon-like Peptide-1_7-36 Amide Mediate Anorexic Responses to Trichothecene Deoxynivalenol and Its Congeners

Toxins, 2022
Type B trichothecenes commonly contaminate cereal grains and include five structurally related congeners: deoxynivalenol (DON), 3-acetyldeoxynivalenol (3-ADON), 15-acetyldeoxynivalenol (15-ADON), fusarenon X (FX), and nivalenol (NIV).
Hui Jia, Zihui Qin, Ben Wei, Xinyi Guo, Huiping Xiao, Huayue Zhang, Zelin Li, Qinghua Wu, Ruibo Zheng, Wenda Wu   +9 more
doaj   +1 more source

A Porcine Monoclonal Antibody Targeting a Conserved GP4 Epitope Protects against In Vivo Infection via the Induction of Broad‐Spectrum PRRSV Neutralization

Advanced Science, EarlyView.
This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen, Jiakai Zhao, Pinpin Ji, Xiaoxuan Li, Hui Niu, Dian Jiao, Lu Zhang, Qianyi Zhu, Xinyu Liu, Julian A. Hiscox, James P. Stewart, Yani Sun, Qin Zhao   +12 more
wiley   +1 more source

Characteristics and outcome of patients with anorexia nervosa on medical nutritional therapy: an institutional study with review of literature

Singapore Medical Journal
Introduction: Eating disorders (EDs) are debilitating mental illnesses that can lead to significant medical complications from malnutrition. Eating disorders are on the rise in Asia and the prevalence is expected to increase. The aim of this study was to
Denise Elizabeth Shi Yun Teo, Valerie Wei Ling Teong, Rajeev Ramachandran, Su Lin Lim, Charlotte Xianghui Lin   +4 more
doaj   +1 more source

Enhancing Anti‐Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression

Advanced Science, EarlyView.
CD19‐293‐EV can switch the CD19 endocytosis pathway from clathrin‐mediated endocytosis to aggregation‐dependent endocytosis, leading to lysosomal degradation of the CD19/EVs complex. Degradation of the EVs leads to impairment in the IFN response and enhancement in EV uptake by target cells, creating a potent feedback cycle.
Zixuan Huang, Chaoqun Lu, Yixin Wang, Huajian Xian, Yuling Zheng, Ting Kang, Rufang Xiang, Shufeng Xie, Minghui Wang, Zeyi Li, Xiaoli Xia, Yaoyifu Yu, Wenjie Zhang, Huijian Zheng, Renyao Pan, Dan Li, Chunjun Zhao, Han Liu   +17 more
wiley   +1 more source

Preoperative Versus Postoperative Chemotherapy With CAPOX Plus Bevacizumab for Resectable Colorectal Liver Metastases: A Randomized Phase II Trial (HiSCO‐01)

Annals of Gastroenterological Surgery, EarlyView.
Our aim was to compare the outcomes of preoperative chemotherapy with postoperative chemotherapy in patients with resectable colorectal liver metastases treated with CAPOX‐Bev. We demonstrated that both preoperative and postoperative CAPOX‐Bev were safely administered, and preoperative chemotherapy showed a numerically higher treatment compliance rate ...
Yuji Takakura, Katsunori Shinozaki, Satoshi Ikeda, Hiroyuki Egi, Yuzo Hirata, Manabu Shimomura, Takafumi Oshiro, Takao Hinoi, Daisuke Sumitani, Masahiro Nakahara, Masanori Yoshimitsu, Naruhiko Honmyo, Tsuyoshi Kobayashi, Junko Tanaka, Hideki Ohdan, on behalf of the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)   +15 more
wiley   +1 more source

Eficacia de los programas preventivos de trastornos alimentarios en adolescentes: análisis bibliográfico

Revista de Estudios e Investigación en Psicología y Educación, 2015
La Organización Mundial de la Salud y la unión Europea en sus estrategias de actuación en materia de salud mental, han incluido la promoción de la salud mental y la prevención de los trastornos mentales como objetivos prioritarios.
Belén Prieto-Castaño, Juan Carlos Fernández-Méndez, Rosa Marianela Salamea-Nieto, Mª Ángeles González-Fernández   +3 more
doaj   +1 more source