Results 61 to 70 of about 360,671 (363)

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

Advanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji, Ruichen Zhang, Dongyi Xu, Patrick C. A. van der Wel, Alessia Lasorsa, Guotai Li, Fangze Guo, Qihui Zhou, Patrick van Rijn   +8 more
wiley   +1 more source

Characteristics and outcome of patients with anorexia nervosa on medical nutritional therapy: an institutional study with review of literature

Singapore Medical Journal
Introduction: Eating disorders (EDs) are debilitating mental illnesses that can lead to significant medical complications from malnutrition. Eating disorders are on the rise in Asia and the prevalence is expected to increase. The aim of this study was to
Denise Elizabeth Shi Yun Teo, Valerie Wei Ling Teong, Rajeev Ramachandran, Su Lin Lim, Charlotte Xianghui Lin   +4 more
doaj   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Eficacia de los programas preventivos de trastornos alimentarios en adolescentes: análisis bibliográfico

Revista de Estudios e Investigación en Psicología y Educación, 2015
La Organización Mundial de la Salud y la unión Europea en sus estrategias de actuación en materia de salud mental, han incluido la promoción de la salud mental y la prevención de los trastornos mentales como objetivos prioritarios.
Belén Prieto-Castaño, Juan Carlos Fernández-Méndez, Rosa Marianela Salamea-Nieto, Mª Ángeles González-Fernández   +3 more
doaj   +1 more source

Seeing Through the Façade of Anorexia: A Grounded Theory of Emotional Change Processes Associated With Recovery From Anorexia Nervosa

Frontiers in Psychiatry, 2022
ObjectivesDifficulties in managing emotions have been implicated in the development and maintenance of anorexia nervosa (AN), and psychological treatment models seek to address this in putative targets of change.
Danielle Drinkwater, Sue Holttum, Tony Lavender, Helen Startup, Anna Oldershaw, Anna Oldershaw   +5 more
doaj   +1 more source

Food addiction in anorexia nervosa: Implications for the understanding of crossover diagnosis [PDF]

, 2022
Isabel Sánchez, Ignacio Lucas, Lucero Munguía, Lucía Camacho‐Barcia, Mònica Giménez, Jéssica Sánchez‐González, Roser Granero, Neus Solé‐Morata, Ashley N. Gearhardt, Carlos Diéguez, Susana Jiménez‐Múrcia, Fernando Fernández‐Aranda   +11 more
openalex   +1 more source

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

A Retrospective Study of First‐Line Immunotherapy for Advanced Non‐Small Cell Lung Cancer in the Elderly

AGING MEDICINE, EarlyView.
This is a retrospective study of the efficacy and safety of first‐line immunotherapy in elderly patients with advanced NSCLC. The hematologic prognostic markers of first‐line immunotherapy in advanced NSCLC patients, especially PNI, were investigated.
Sheng Yang, Yalin Zhu, Sitong Liu, Kui Xiao   +3 more
wiley   +1 more source

Risk factors for anorexia nervosa: A population‐based investigation of sex differences in polygenic risk and early life exposures [PDF]

, 2023
Hannah Chatwin, K. E. Van Holde, Zeynep Yılmaz, Janne Tidselbak Larsen, Clara Albiñana, Bjarni J. Vilhjálmsson, Preben Bo Mortensen, Laura M. Thornton, Cynthia M. Bulik, Liselotte Petersen   +9 more
openalex   +1 more source

Impact of Low Preoperative Prognostic Immune Nutritional Index on Survival and Postoperative Infectious Complications in Patients With Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The prognostic immune nutritional index (PINI) is increasingly recognized for its potential clinical utility. However, multifaceted evaluations of its ability to predict oncological outcomes in colorectal cancer (CRC) and its association with postoperative infectious complications remain limited.
Shinji Yamashita, Yoshinaga Okugawa, Hiroki Imaoka, Tadanobu Shimura, Takahito Kitajima, Mikio Kawamura, Yoshiki Okita, Masaki Ohi, Minako Kobayashi, Yuji Toiyama   +9 more
wiley   +1 more source